Aging and electrocortical response to error feedback during a spatial learning task
Aging and electrocortical response to error feedback during a spatial learning task
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DOI：
10.1111/j.1469-8986.2008.00699.x
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发表时间：
2008-11-01
期刊：
影响因子：
3.7
通讯作者：
Segalowitz, Sidney J.
中科院分区：
文献类型：
--
作者：
Mathewson, Karen J.;Dywan, Jane;Segalowitz, Sidney J.
事件相关电位收集老年人和年轻人的错误反馈的适应格罗顿迷宫学习测试，年龄敏感的空间学习和执行技能的措施，预计最大限度地涉及前扣带皮层（ACC）。老年人比年轻对照组犯更多的错误，产生更小的反馈相关负性（FRN）。LORETA源定位显示，对于年轻人，与FRN相关的神经激活集中在ACC，并且对负反馈更强。老年人的ACC激活强度和分化程度较低，但FRN振幅与最困难的迷宫的错误率有关。反馈P3对负反馈敏感，但对两组的错误预测都没有作用。这些数据反映了ACC反应的选择性年龄相关性下降，但也反映了其对老龄化性能监测的持续贡献。
Event-related potentials were collected as older and younger adults responded to error feedback in an adaptation of the Groton Maze Learning Test, an age-sensitive measure of spatial learning and executive skills expected to maximally involve anterior cingulate cortex (ACC). Older adults made more errors and produced smaller feedback-related negativities (FRNs) than young controls. LORETA source localization revealed that, for young adults, neural activation associated with the FRN was focused in ACC and was stronger to negative feedback. Older adults responded with less intense and less differentiated ACC activation, but FRN amplitudes did relate to error rate for the most difficult mazes. The feedback P3 was sensitive to negative feedback but played no role in the prediction of error for either group. These data reflect the selective age-related decline of ACC response but also its continued contribution to performance monitoring in aging.