wblA, a pleiotropic regulatory gene modulating morphogenesis and daptomycin production in Streptomyces roseosporus
wblA, a pleiotropic regulatory gene modulating morphogenesis and daptomycin production in Streptomyces roseosporus
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wblA，一种调节玫瑰孢链霉菌形态发生和达托霉素产生的多效性调控基因
DOI：
10.1111/jam.13512
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发表时间：
2017-09-01
影响因子：
4
通讯作者：
Liao, G.
中科院分区：
文献类型：
--
作者：
Huang, X.;Ma, T.;Liao, G.
在达托霉素生产者玫瑰孢链霉菌的测序基因组中鉴定了编码WhiB家族蛋白的同源物的wblA基因。为了探讨wblA的功能，我们构建了wblA缺失菌株、wblA互补菌株和wblA过表达菌株，检测其是否影响次生代谢产物的产生和形态建成。
The wblA gene, encoding a homologue of the WhiB family protein, was identified in the sequenced genome of daptomycin producer Streptomyces roseosporus. To explore the function of wblA, we construct wblA disruption strains, complemented strains and overexpression strains to test whether it can affect the production of secondary metabolites and morphogenesis.