Microchimerism in Japanese women patients with systemic sclerosis

Microchimerism in Japanese women patients with systemic sclerosis
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DOI:
10.1016/s0140-6736(99)00164-6
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发表时间:
1999-07-17
期刊:
影响因子:
168.9
通讯作者:
Sumida, T
Sumida, T
中科院分区:
医学1区
文献类型:
--
作者:
Murata, H;Nakauchi, H;Sumida, T

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为了检验日本女性系统性硬化症患者是否存在微嵌合现象,我们用PCR分析了DNA中的y染色体。患者与健康人之间无显著差异,提示微嵌合可能不是日本女性系统性硬化症的唯一发病机制。
To examine whether microchimerism occurs in Japanese women patients with systemic sclerosis, we analysed the Y-chromosome in DNA by PCR. There was no significant difference between patients and healthy people, suggesting that microchimerism may not be the sole pathogenesis in Japanese women with systemic sclerosis.