Predictive accuracy of the Framingham coronary risk score in British men: prospective cohort study
Predictive accuracy of the Framingham coronary risk score in British men: prospective cohort study
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DOI：
10.1136/bmj.327.7426.1267
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发表时间：
2003-11-29
影响因子：
105.7
通讯作者：
Ebrahim, S
中科院分区：
文献类型：
--
作者：
Brindle, P;Emberson, J;Ebrahim, S
目的建立一个具有代表性的英国人群中冠心病的Fragrance风险评分的预测准确性。设计前瞻性队列研究。设置在英国的24个城镇。参与者6643名40-年龄59岁，在进入英国区域心脏研究时无心血管疾病。主要结果指标比较观察到的10年冠心病死亡率和事件结果在6643名男性中，2.8%（95%可信区间2.4%~ 3.2%）死于冠心病，而预测值为4.1%（相对高估47%，P
Objective To establish the predictive accuracy of the Framingham risk score for coronary heart disease in a representative British population.Design Prospective cohort study.Setting 24 towns in the United Kingdom.Participants 6643 British men aged 40-59 years and free from cardiovascular disease at entry into the British regional heart study.Main outcome measures Comparison of observed 10 year coronary heart disease mortality and event rates with predicted rates for each individual, using the relevant Framingham risk equation.Results Of 6643 men, 2.8% (95% confidence interval 2.4% to 3.2%) died from coronary heart disease compared with 4.1% predicted (relative overestimation 47%, P