Disparities in Liver Cancer Occurrence in the United States by Race/Ethnicity and State
Disparities in Liver Cancer Occurrence in the United States by Race/Ethnicity and State
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DOI：
10.3322/caac.21402
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发表时间：
2017-07-01
影响因子：
254.7
通讯作者：
Jemal, Ahmedin
中科院分区：
文献类型：
--
作者：
Islami, Farhad;Miller, Kimberly D.;Jemal, Ahmedin
肝癌是高度致命的，美国的死亡率比任何其他癌症都增长得快，自20世纪80年代中期以来翻了一番。据估计，2017年，该疾病将在美国造成约41，000例新发癌症病例和29，000例癌症死亡。在本文中，来自监测，流行病学和最终结果（SEER）计划和国家卫生统计中心的数据用于提供肝癌发病率，死亡率和生存率和趋势的概述，包括种族/民族和州的数据。肝癌主要危险因素的患病率也是根据疾病控制和预防中心的全国调查数据报告的。尽管近几十年来肝癌生存率有所提高，但只有五分之一的患者在诊断后存活5年。肝癌死亡率按种族/民族（从非西班牙裔白人的5.5/100，000到美洲印第安人/阿拉斯加原住民的11.9/100，000）和州（从北达科他州的3.8/100，000到哥伦比亚特区的9.6/100，000）以及州内的种族/民族存在显著差异。风险因素患病率的差异是观察到的肝癌发病率变化的主要原因。因此，与日益增加的负担相反，通过有针对性地应用现有的预防、早期发现和治疗知识，包括改进B型肝炎病毒的疫苗接种，筛查和治疗慢性丙型肝炎病毒感染，保持健康的体重，获得高质量的糖尿病护理，防止过度饮酒，并在州和国家一级控制烟草。(C)2017美国癌症协会
Liver cancer is highly fatal, and death rates in the United States are increasing faster than for any other cancer, having doubled since the mid-1980s. In 2017, it is estimated that the disease will account for about 41,000 new cancer cases and 29,000 cancer deaths in the United States. In this article, data from the Surveillance, Epidemiology, and End Results (SEER) Program and the National Center for Health Statistics are used to provide an overview of liver cancer incidence, mortality, and survival rates and trends, including data by race/ethnicity and state. The prevalence of major risk factors for liver cancer is also reported based on national survey data from the Centers for Disease Control and Prevention. Despite the improvement in liver cancer survival in recent decades, only 1 in 5 patients survives 5 years after diagnosis. There is substantial disparity in liver cancer death rates by race/ethnicity (from 5.5 per 100,000 in non-Hispanic whites to 11.9 per 100,000 in American Indians/Alaska Natives) and state (from 3.8 per 100,000 in North Dakota to 9.6 per 100,000 in the District of Columbia) and by race/ethnicity within states. Differences in risk factor prevalence account for much of the observed variation in liver cancer rates. Thus, in contrast to the growing burden, a substantial proportion of liver cancer deaths could be averted, and existing disparities could be dramatically reduced, through the targeted application of existing knowledge in prevention, early detection, and treatment, including improvements in vaccination against hepatitis B virus, screening and treatment for chronic hepatitis C virus infections, maintaining a healthy body weight, access to high-quality diabetes care, preventing excessive alcohol drinking, and tobacco control, at both the state and national levels. (C) 2017 American Cancer Society.