The circadian system of Chlamydomonas reinhardtii
The circadian system of Chlamydomonas reinhardtii
复制标题
莱茵衣藻的昼夜节律系统
DOI：
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
M. Mittag
中科院分区：
文献类型：
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作者：
Dobromir Iliev;Olga Voystekh;M. Mittag
摘要在单细胞真核绿色衣藻莱茵衣藻中，几种昼夜节律在生理学上已得到很好的表征。最近，整个核，叶绿体和线粒体的基因组已被测序，并已创建约20万个表达序列标签。因此，昼夜节律系统的功能蛋白质组学已经开始，并导致在识别的昼夜节律系统的新组件（蛋白质二硫键异构酶和tetratricopeptide重复蛋白）。此外，还对C. reinhardtii基因组与其他模式生物已知的时钟相关基因的比较表明，一些光感受器，特别是时钟相关的激酶和磷酸酶在C.莱因哈德氏菌在C. reinhardtii，其时间表达在转录水平控制。此外，昼夜节律RNA结合蛋白（CHLAMY 1）已被表征。它代表了一种新型的RNA结合蛋白，并在转录后水平介导昼夜节律控制。其昼夜节律结合活性似乎是由差异多蛋白复合物控制。
Abstract In the unicellular eukaryotic green alga Chlamydomonas reinhardtii, several circadian rhythms have been physiologically well characterised. Recently, the entire nuclear, chloroplast and mitochondrial genomes of this alga have been sequenced, and about 200 000 expressed sequence tags have been created. Therefore, functional proteomics of the circadian system has been initiated and has resulted in the identification of novel components of the circadian system (a protein disulfide isomerase and a tetratricopeptide repeat protein). Furthermore, comparative analysis of the C. reinhardtii genome with known clock-related genes from other model organisms reveals that some photoreceptors and especially clock-related kinases and phosphatases are well conserved in C. reinhardtii. Several circadian expressed genes have been identified in C. reinhardtii, whose temporal expression is controlled at the transcriptional level. Also, a circadian RNA-binding protein (CHLAMY 1) has been characterised. It represents a novel type of RNA-binding protein and mediates circadian control at the post-transcriptional level. Its circadian binding activity appears to be controlled by differential multi-protein complexes.
影响因子：
4
作者：
Pinfen Yang;L. Fox;R. Colbran;W. Sale
通讯作者：
Pinfen Yang;L. Fox;R. Colbran;W. Sale
CABII 的转录受莱茵衣藻生物钟的调节。
影响因子：
5.1
作者：
Jacobshagen,S;Kindle,KL;Johnson,CH
通讯作者：
Johnson,CH