Effect of acute heat exposure on skin blood flow of the paralyzed thigh in persons with spinal cord injury
Effect of acute heat exposure on skin blood flow of the paralyzed thigh in persons with spinal cord injury
复制标题
急性热暴露对脊髓损伤患者瘫痪大腿皮肤血流的影响
DOI：
10.1038/sj.sc.3100988
复制
发表时间：
2000
期刊：
影响因子：
2.2
通讯作者：
S. Muraki
中科院分区：
文献类型：
--
作者：
M. Yamasaki;M. Shiokawa;S. W. Choi;S. Muraki
目的：研究高温暴露过程中体温升高是否会促进脊髓损伤患者大腿皮肤血流量（SBFT）。研究设计：一项前瞻性研究，高病变和低病变。设置：广岛大学，东广岛，日本。方法：7名男性截瘫患者（T5-L2）和7名身体健全的受试者自愿参加实验。首先，受试者在25 ℃的环境温度（Ta）和50%的相对湿度（Rh）下休息1小时。此后，将受试者移至加热至Ta为33 ℃和Rh为50-55%的气候室中，并暴露于该环境1小时。结果：4例Th 6 ~ Th 10期高病变组（HL组）SBFT无明显升高，而3例Th 11或Th 12期低病变组（LL组）SBFT升高。虽然Tty随着热暴露时间的增加而增加，但在任何一个截瘫组中，Tty和SBFT之间的相关性都不显著。然而，SBFT和Tthigh之间的相关性在两组中都非常显著。Tthigh在LL中的增加是由于增加的大腿皮肤血流量，而在HL中，它被认为是由于从环境到skin.Conclusion热传递：这些研究结果表明，SBFT在热暴露过程中在很大程度上取决于脊髓损伤的水平。SBFT与低病变增加热暴露时，大腿的交感神经皮肤血管供应被保存。
Objectives: To investigate whether increased body temperature during heat exposure promotes skin blood flow of the thigh (SBFT) in individuals with spinal cord injury at rest.Study design: A prospective study with high lesion and with low lesion.Setting: Hiroshima University, Higashi-Hiroshima, Japan.Methods: Seven male paraplegics (T5-L2) and seven able-bodied subjects volunteered to participate in the experiment. First the subject rested for 1 h at an ambient temperature (Ta) of 25 C and a relative humidity (Rh) of 50%. Thereafter, the subject moved to a climatic chamber heated to Ta of 33 C an Rh of 50–55% and was exposed to this environment for 1 h. SBFT, stroke volume, heart rate, the skin temperature of the medial thigh (Tthigh) and the tympanic membrane temperature (Tty) were assessed during the experiment.Results: The four subjects with high lesions between Th6 and Th10 (HL) showed no increase in SBFT, while the remaining three subjects with low lesion at Th11 or Th12 (LL) showed increased SBFT in the hot environment. Although Tty increased with exposure time in heat, correlation between Tty and SBFT was not significant in either paraplegic group. However, correlation between SBFT and Tthigh was highly significant in both groups. The increase in Tthigh in LL was due to increased skin blood flow in the thigh, while in HL it was considered attributable to heat transfer from the environment to the skin.Conclusion: These findings indicate that SBFT during heat exposure was largely dependent on the level of spinal cord injury. SBFT with low lesions increased during heat exposure when the sympathetic cutaneous vasomotor supply of the thigh was preserved.