Endocrine and metabolic adaptation following caesarean section or vaginal delivery
Endocrine and metabolic adaptation following caesarean section or vaginal delivery
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DOI：
10.1136/fn.74.2.f132
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发表时间：
1996-03-01
影响因子：
4.4
通讯作者：
Symonds, ME
中科院分区：
文献类型：
--
作者：
Bird, JA;Spencer, JAD;Symonds, ME
比较三组婴儿的内分泌情况（脐静脉血浆）。在8次阴道分娩、11次分娩过程中的紧急剖腹产和13次分娩前的择期剖腹产后采集样本。平均脐带血浆浓度的甲状腺素和三碘甲状腺原氨酸显着较高，皮质醇浓度较低，择期剖腹产后，与两个劳动组相比。平均脐带血浆促甲状腺激素（TSH）浓度显着降低阴道分娩后择期剖腹产术相比，这些结果表明，劳动降低血浆甲状腺激素浓度在出生时与皮质醇的上升。这些适应可能是刺激随后激增的三碘甲状腺原氨酸先前报道发生在出生后的前几个小时内阴道分娩的婴儿。
The endocrine profile (umbilical venous plasma) of three groups of infants was compared. Samples were taken after eight vaginal deliveries, 11 emergency caesarean sections during labour, and 13 elective caesarean sections before labour. Mean umbilical plasma concentrations of thyroxine and triiodothyronine were significantly higher and cortisol concentration were lower after elective caesarean section compared with the two labour groups. Mean umbilical plasma thyroid stimulating hormone (TSH) concentration was significantly lower after vaginal delivery compared with elective caesarean section.These results suggest that labour reduces plasma thyroid hormone concentrations at birth in association with a rise in cortisol. These adaptations may be the stimulus for the subsequent surge in triiodothyronine previously reported to occur over the first few hours after birth in vaginally delivered infants.