Pathogenesis and pathophysiology of endometriosis.
Pathogenesis and pathophysiology of endometriosis.
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DOI:
10.1016/j.fertnstert.2012.06.029
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发表时间:
2012-09
影响因子:
6.7
通讯作者:
Giudice, Linda C.
中科院分区:
文献类型:
--
作者:
Burney, Richard O.;Giudice, Linda C.
Originally described over three hundred years ago, endometriosis is classically defined by the presence of endometrial glands and stroma in extrauterine locations. Endometriosis is an inflammatory, estrogen dependent condition associated with pelvic pain and infertility. This work reviews the disease process from theories regarding origin to the molecular basis for disease sequelae. A thorough understanding of the histopathogenesis and pathophysiology of endometriosis is essential toward the development of novel diagnostic and treatment approaches for this debilitating condition.
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