Ventricular enlargement in schizophrenia: definition and prevalence.
Ventricular enlargement in schizophrenia: definition and prevalence.
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精神分裂症的心室扩大：定义和患病率。
DOI：
10.1176/ajp.139.3.292
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Olsen,SA
中科院分区：
文献类型：
--
作者：
Andreasen,NC;Smith,MR;Jacoby,CG;Dennert,JW;Olsen,SA
三个不同的研究小组已经描述了精神分裂症心室扩大的心室脑比（VBR）。由于样本可能不能代表广泛的精神分裂症患者群体，因此提出了关于普遍性的问题。作者报告了一个严格定义但具有代表性的间歇性住院但生活在社区的精神分裂症患者的心室扩大。他们提供了额外的证据表明，心室扩大确实发生在精神分裂症患者中，尽管其发生率不像以前报道的那样高。心室扩大的定义，以及采样和选择的控制组的影响有关的问题进行了讨论。
Ventricular enlargement in schizophrenia as measured by ventricular-brain ratio (VBR) has been described by three different research groups. Because of the possibility that the samples might not be representative of the broad population of schizophrenic patients, questions have been raised about generalizability. The authors report on ventricular enlargement in a rigorously defined but representative sample of schizophrenic patients intermittently hospitalized but living in the community. They provide additional evidence that ventricular enlargement does occur in schizophrenic patients, although not at rates as high as those previously reported. Issues related to the definition of ventricular enlargement, as well as the effects of sampling and choice of a control group, are discussed.