Ultrathin monolithic 3D printed optical coherence tomography endoscopy for preclinical and clinical use
Ultrathin monolithic 3D printed optical coherence tomography endoscopy for preclinical and clinical use
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DOI：
10.1038/s41377-020-00365-w
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发表时间：
2020-07-20
影响因子：
19.4
通讯作者：
McLaughlin, Robert A.
中科院分区：
文献类型：
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作者：
Li, Jiawen;Thiele, Simon;McLaughlin, Robert A.
临床前和临床诊断越来越依赖于通过内窥镜以高分辨率可视化内部器官的技术。微型内窥镜探头是必要的成像小腔或微妙的器官，而不会造成创伤的组织。然而，目前的制造方法限制了高度小型化探针的成像性能，限制了其广泛应用。为了克服这一限制，我们开发了一种新的MEMS探针制造技术，该技术利用3D微打印来可靠地创建面向侧面的自由形式的微光学器件（
Preclinical and clinical diagnostics increasingly rely on techniques to visualize internal organs at high resolution via endoscopes. Miniaturized endoscopic probes are necessary for imaging small luminal or delicate organs without causing trauma to tissue. However, current fabrication methods limit the imaging performance of highly miniaturized probes, restricting their widespread application. To overcome this limitation, we developed a novel ultrathin probe fabrication technique that utilizes 3D microprinting to reliably create side-facing freeform micro-optics (