ULTRASTRUCTURAL DIFFERENTIATION DURING DROSOPHILA NEUROGENESIS INVITRO

ULTRASTRUCTURAL DIFFERENTIATION DURING DROSOPHILA NEUROGENESIS INVITRO
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DOI:
10.1002/neu.480070507
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发表时间:
1976-01-01
期刊:
JOURNAL OF NEUROBIOLOGY
影响因子:
--
通讯作者:
TEPLITZ, RL
TEPLITZ, RL
中科院分区:
其他
文献类型:
--
作者:
GERSON, I;SEECOF, RL;TEPLITZ, RL

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D.黑腹神经母细胞在体外分化,并且每个产生约18个子神经元的簇。单个簇的EM观察显示,来自子神经元的轴突在细胞体簇内形成神经堆。神经桩的大小和复杂性增加了几个小时,在此期间,神经突之间形成化学突触,可能是电紧张性突触。直径约为0.4的透明囊泡35 nm的致密核心囊泡和直径约35 nm的致密核心囊泡。检测60和160 nm。神经桩的发展表明,先决条件的细胞识别现象在体外分化过程中表现出来,神经桩的复杂性表明它可能已经获得了处理信息的能力。
D. melanogaster neuroblasts differentiate in vitro, and each gives rise to a cluster of about 18 daughter neurons. EM observations of single clusters show that axons from daughter neurons form a neuropile within the cluster of cell bodies. The neuropile increases in size and complexity for several hours during which time chemical, and probably electrotonic, synapses form between neurites. Clear vesicles with diameters of .apprx. 35 nm and dense core vesicles with diameters of .apprx. 60 and 160 nm were detected. The development of the neuropile indicates that the prerequisite cell recognition phenomena were manifested during differentiation in vitro, and the complexity of the neuropile suggests it may have attained the capacity to process information.