PET detectors with 127 ps CTR for the Tachyon-II time-of-flight PET scanner.
PET detectors with 127 ps CTR for the Tachyon-II time-of-flight PET scanner.
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用于 Tachyon-II 飞行时间 PET 扫描仪的 PET 探测器，CTR 为 127 ps。
DOI：
10.1016/j.nima.2019.03.083
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Peng,Qiyu
中科院分区：
文献类型：
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作者：
Xie,Siwei;Zhang,Xi;Peng,Hui;Yang,Jingwu;Huang,Qiu;Xu,Jianfeng;Peng,Qiyu
正电子发射断层扫描（PET）重建图像的信噪比（SNR）可以通过定时测量来提高。在这篇文章中，我们设计，制造和测试了32个飞行时间（TOF）探测器的第二代Tachyon TOF-PET扫描仪。探测器模块由两个6× 6× 6 mm 3的2× 12氧硅酸镥钇（LYSO）晶体立方体阵列组成。用光学胶将离散晶体耦合到6 mm硅光电倍增管（SiPM）。测试所有SiPM的暗电流。为了校正时移引起的时间测量误差，提出了两种基于能量与时间信息关系的补偿方法（对数校正和线性校正）。作为比较，SiPM阵列耦合到4 mm和6 mm侧晶体立方体没有光学胶进行了测试的符合时间分辨率（CTR）。在偏置电压为31.5 V、温度为20° C（±1° C）时，1536个测试SiPM暗电流的平均值和标准偏差（SD）为12.72+/-1.70 μ A。通过对数校正，CTR性能在窄能量窗口内提高了1.5%，在宽能量窗口内提高了1.10%。对于768对测试的SiPM，6 mm侧边晶体立方体胶耦合的CTR的平均值和SD为126.9+/-3.6 ps。该探测器有望为采用多层探测器的下一代超快CTR商用PET扫描仪提供技术参考。
The signal-to-noise ratio (SNR) of the reconstructed image of Positron Emission Tomography (PET) can be improved by the timing measurement. In this article, we designed, fabricated and tested 32 time-of-flight (TOF) detectors for the second generation of Tachyon TOF-PET scanners. The detector module consists of two arrays of 2× 12 lutetium–yttrium oxyorthosilicate (LYSO) crystal cubes of 6× 6× 6 mm 3. The discrete crystals were coupled to the 6 mm silicon photomultipliers (SiPMs) with optical glue. All the SiPM were tested for dark current. To correct the errors in the timing measurements caused by time-walk, two compensation methods (log-correction and linear-correction) based on the relationship between energy and timing information were purposed. As a comparison, the SiPM arrays coupled to 4 mm and 6 mm side crystal cube without optical glue were tested for coincidence timing resolution (CTR). The mean and standard deviations (SD) of dark current for the 1536 tested SiPMs were 12.72+/-1.70 μ A at the bias voltage of 31.5 V and the temperature of 20° C (±1° C). CTR performance has increased by∼ 5% within a narrow energy window, and∼ 10% in a wide energy window by log-correction. The mean and SD of the CTR of 6 mm side crystal cube glue coupled was 126.9+/-3.6 ps for the 768 pairs of tested SiPMs. The detector is expected to provide a technical reference for the next generation of ultra-fast CTR commercial PET scanner using multilayer detectors.