Functional imaging of the thalamus in language.
Functional imaging of the thalamus in language.
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DOI：
10.1016/j.bandl.2012.06.004
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发表时间：
2013-07
影响因子：
2.5
通讯作者：
Llano DA
中科院分区：
文献类型：
--
作者：
Llano DA
在此，回顾了有关语言任务期间丘脑功能成像的文献。五十项研究符合分析标准。与丘脑激活相关的两个最常见的任务范例是生成任务（例如单词或句子生成）和命名，尽管激活也出现在涉及词汇决策、阅读和工作记忆的任务中。通常，丘脑激活是双侧的，左侧大于右侧，同时额叶和颞叶皮质区域也有激活。尽管很少有研究将丘脑激活与注意力或任务难度的测量严格相关，但丘脑激活与感知上具有挑战性的任务有关。激活位点的峰值几乎出现在所有丘脑区域，偏向于左侧和中线激活。这些分析表明丘脑可能参与涉及词汇信息操作的过程，但也指出需要使用语言任务对丘脑进行更系统的研究。
Herein, the literature regarding functional imaging of the thalamus during language tasks is reviewed. Fifty studies met criteria for analysis. Two of the most common task paradigms associated with thalamic activation were generative tasks (e.g. word or sentence generation) and naming, though activation was also seen in tasks that involve lexical decision, reading and working memory. Typically, thalamic activation was seen bilaterally, left greater than right, along with activation in frontal and temporal cortical regions. Thalamic activation was seen with perceptually challenging tasks, though few studies rigorously correlated thalamic activation with measures of attention or task difficulty. The peaks of activation loci were seen in virtually all thalamic regions, with a bias towards left-sided and midline activation. These analyses suggest that the thalamus may be involved in processes that involve manipulations of lexical information, but point to the need for more systematic study of the thalamus using language tasks.