Magnetic resonance imaging of the hypothalamic-neurohypophyseal system
Magnetic resonance imaging of the hypothalamic-neurohypophyseal system
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DOI：
10.1111/j.0953-8194.2004.01183.x
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发表时间：
2004-04-01
影响因子：
3.2
通讯作者：
Fujisawa, I
中科院分区：
文献类型：
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作者：
Fujisawa, I
磁共振成像 (MRI) 是下丘脑-神经垂体系统 (HNS) 诊断成像的革命性进步。使用 MRI 可以清楚地看到鞍区和鞍旁区域的详细解剖结构，因为它没有骨伪影和多方向能力。垂体后叶在 MR T1 加权图像 (T1WI) 上显示出特征性亮信号，并且与前叶明显分离。中枢性尿崩症患者不存在该亮信号，并且被认为反映了后叶中正常的加压素储存。 T1W1 上后叶与脑桥的信号强度比与后叶中加压素含量密切相关。除了形态学评估之外，MRI 还提供有关 HNS 功能的独特信息。本文展示了 HNS 的 MRI 表现（正常情况、中枢性尿崩症、后叶耗竭、后叶异位以及垂体柄神经分泌小泡的阻塞现象）。
Magnetic resonance imaging (MRI) is a revolutionary advance in diagnostic imaging of the hypothalannic-neurohypophyseal system (HNS). The detailed anatomy of the sellar and parasellar region is clearly visible using MRI, because it has no bony artifacts and multidirectional capability. The posterior lobe of the pituitary gland displays a characteristic bright signal on the MR T1-weighted image (T1WI), and is distinctly separated from the anterior lobe, The bright signal is absent in patients with central diabetes insipidus, and is thought to reflect normal vasopressin storage in the posterior lobe. The signal intensity ratio of the posterior lobe to the pons on T1Wl is strongly correlated with vasopressin content in the posterior lobe. In addition to the morphological evaluation, MRI provides unique information concerning the function of the HNS. The MRI findings of the HNS (normal condition, central diabetes insipidus, a depleted posterior lobe, an ectopic posterior lobe, and a damming-up phenomenon of the neurosecretory vesicles in the pituitary stalk) are demonstrated in this article.