Sea urchin histone mRNA termini are located in gene regions downstream from putative regulatory sequences
Sea urchin histone mRNA termini are located in gene regions downstream from putative regulatory sequences
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海胆组蛋白 mRNA 末端位于假定调控序列下游的基因区域
DOI：
10.1038/285147a0
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发表时间：
1980
期刊：
影响因子：
64.8
通讯作者：
M. Birnstiel
中科院分区：
文献类型：
--
作者：
C. Hentschel;J. Irminger;P. Bucher;M. Birnstiel
S1核酸酶图谱分析发现，沙尺蠖胚胎组蛋白mRNAs的5′端位于或邻近一个短序列同源性（5′ pyCATTCpu 3 ′）下游，该同源性位于假定的RNA聚合酶II调控序列（5′ TATAAATA 3 ′）或相关序列。3′末端图谱刚好位于含有富含GC的连字符二分体对称性的序列之后，这是大多数已知终止子序列的特征。
S1 nuclease mapping of the Psammechinus miliaris embryonic histone mRNAs locates the 5′ termini in or adjacent to a short sequence homology (5′ pyCATTCpu3′) downstream from the putative RNA polymerase II regulatory sequence (5′TATAAATA3′) or related sequences. The 3′ termini map just after a sequence containing GC-rich hyphenated dyad symmetry, a feature of most known terminator sequences.