P-346?First comparison of the egg freezing and storage cost between medical adaptation and social adaptation of Japan fertility hospitals and clinics based on institution's websites
P-346?First comparison of the egg freezing and storage cost between medical adaptation and social adaptation of Japan fertility hospitals and clinics based on institution's websites
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P-346？首次基于机构网站比较日本生育医院和诊所医疗适应和社会适应的卵子冷冻和储存成本
DOI：
10.1093/humrep/deac107.329
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发表时间：
2022
影响因子：
6.1
通讯作者：
Terada Y
中科院分区：
文献类型：
--
作者：
Shirasawa H;Kumazawa Y;Sato W;Togashi K;Ono N;Fujishima A;Terada Y
研究问题在日本，医疗和社会卵子冷冻保存生育能力的冷冻费用和每年的储存费用是多少在机构的网站上明确公布？概要回答在621家不孕不育治疗机构中，有146家在网站上列出了卵子冷冻费用，46家明确了冷冻费用，71家明确了每年的保存费用。目前已知的情况在日本，从2022年4月起，标准的辅助生殖技术将纳入保险范围，但医疗和社会卵子冷冻仍将继续由私人出资。因此，目前尚不清楚日本有多少设施进行卵子冷冻。此外，虽然冷冻和每年储存的成本因设施而异，但没有数据比较日本或其他国家的设施之间的卵子冷冻。研究设计、规模、持续时间本研究是一项基于网络的调查，由日本生殖医学会认证的单一委员会专家于2021年10月详尽浏览了日本所有621家生育治疗机构的网站，并分析了卵子冷冻的实施情况，网站上清楚地说明了卵子的冷冻费用和每年的储存费用。受试者/材料、设置、方法在621家机构中，将88家在其网站上明确表示提供卵子冷冻的医疗原因的机构分为医疗组，将58家明确表示提供卵子冷冻的社会原因的机构分为社会组进行统计分析。我们比较了冷冻和每年的存储成本，分别，它是否取决于鸡蛋的数量或是否是一个固定cost.Main结果和机会的作用621个机构，146（23.5%），88在医疗组和58在社会组，指定他们提供卵子冷冻。在网站上对冷冻费用和年储存费用的澄清率，医疗组分别为27.3%和30.7%，社会组分别为72.4%和75.9%，社会组高于医疗组（P < 0.01）。卵子冷冻的固定费用百分比在社会组（6/42，14.3%）显著低于医疗组（9/24，37.5%）（p < 0.05）。固定费用占年储存费用的百分比，社会组（30/44，68.2%）显著低于医疗组（25/27，92.6%）（P < 0.05）。对于1、5和10个卵子，平均冷冻成本/年储存成本如下。医疗组为（JPY 45，527/JPY 22，327，JPY 65，179/JPY 22，530，JPY 90，311/JPY 22，770），社会组为（JPY 56，822/JPY 40，178，JPY 88，429/JPY 56，502，JPY 136，550/JPY 79，090），因此社会组在每种情况下的费用金额明显最高。请注意，1万日元约为77.7欧元。最贵的诊所储存10个卵子是50万日元（3，883欧元），最低的大学医院为4，600日元（EUR35.7）每年。局限性，谨慎的理由本次调查是通过仔细浏览设施的网站进行的，但由于我们没有通过问卷或电子邮件确认信息，有可能信息已经更新。另一个限制是，不到一半的医疗团体在他们的网站上列出了成本细节。
Study questionIn Japan, how much of freezing cost and the yearly storage cost of medical and social egg freezing for fertility preservation is clearly disclosed on the institution's website?Summary answerOf the 621 infertility treatment institutions, 146 listed egg freezing on their websites, 46 specified the freezing cost, and 71 specified the yearly storage cost.What is known alreadyIn Japan, from April 2022, standard assisted reproductive technology will be covered by insurance, but medical and social egg freezing will continue to be privately funded. Therefore, it is unclear how many facilities in Japan perform egg freezing. Furthermore, while the cost of freezing and yearly storage varies significantly from facility to facility, there has been no data comparing egg freezing among facilities in Japan or other countries. Therefore, we extracted data about freezing and storage cost from each institution's website and compared them for the first time.Study design, size, durationThis study is a web-based survey in which a single board-certified specialist by Japan Society for Reproductive Medicine exhaustively browsed the websites of all 621 fertility treatment institutions in Japan in October 2021 and analyzed the implementation of egg freezing, freezing costs, and yearly storage costs of egg are clearly stated on the websites. The costs of drugs used for egg retrieval and ovarian stimulation were excluded.Participants/materials, setting, methodsOf the 621 institutions, 88 institutions that clearly stated on their websites that they offer egg freezing for medical reasons were divided into a medical group, and 58 institutions that clearly stated that they offer egg freezing for only social reasons were divided into social group for statistical analysis. We compared the freezing and the yearly storage cost, respectively, whether it varies depending on the number of eggs or whether it is a fixed cost.Main results and the role of chanceOf the 621 institutions, 146 (23.5%), 88 in the medical group and 58 in the social group, specified that they offer egg freezing. The percentages of clarification for freezing cost and yearly storage cost on the website were 27.3% and 30.7% in the medical group, 72.4%, and 75.9% in the social group, so the social group was higher in both cases (p < 0.01). The percentage of fixed costs for egg freezing was significantly lower in the social group (6/42, 14.3%) than in the medical group (9/24, 37.5%) (p < 0.05). The percentage of fixed costs for yearly storage cost was samely significantly lower in the social group (30/44, 68.2%) than in the medical group (25/27, 92.6%) (p < 0.05). The mean freezing cost/yearly storage cost was as follows for 1, 5, and 10 eggs. The medical group was (JPY45,527/JPY22,327, JPY65,179/JPY22,530, JPY90,311/JPY22,770), and the social group was (JPY56,822/JPY40,178, JPY88,429/JPY56,502, JPY136,550/JPY79,090), so the social group had the significantly highest amount of costs in each case. Note that JPY 10,000 is about EUR77.7. The most expensive clinic to store ten eggs was JPY500,000 (EUR3,883) per year, and the least university hospital was JPY 4,600 (EUR35.7) per year.Limitations, reasons for cautionThis survey was conducted by carefully browsing the facility's website, but since we did not confirm the information through questionnaires or e-mail, there is the possibility that the information may have been updated. Another limitation is that less than half of the medical groups list cost details on their websites.Wider implications of the findings …