Homogeneously staining chromosome regions and double minutes in a mouse adrenocortical tumor cell line.
Homogeneously staining chromosome regions and double minutes in a mouse adrenocortical tumor cell line.
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对小鼠肾上腺皮质肿瘤细胞系中的染色体区域和双分钟进行均匀染色。
DOI：
10.1159/000131535
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
Francke,U
中科院分区：
文献类型：
--
作者：
George,DL;Francke,U
我们使用多种显带技术分析了分泌类固醇的小鼠肾上腺肿瘤细胞系Y1的两个亚系的染色体含量。其中一个亚系含有标记染色体，带有大的“均一染色区”(HSRs)。另一条副线包含许多双分钟，但没有高铁。两个亚系共有的标记染色体的存在表明它们来自共同的前体。这两个亚系核型稳定，生长速度相似，Δ5，3β-羟基类固醇脱氢酶染色阳性。
We have used a number of banding techniques to analyze the chromosomal content of two sublines of the steroid-secreting mouse adrenocortical tumor cell line Y1. One of the sublines contains marker chromosomes with large “homogeneously staining regions” (HSRs). The other subline contains numerous double minutes, but no HSR. The presence of marker chromosomes shared by both sublines indicates their derivation from a common precursor. Both sublines are karyotypically stable, have similar growth rates, and exhibit positive staining for Δ5,3β-Hydroxysteroid dehydrogenase.