The Quick Inventory of Depressive Symptomatology-Self-report: a psychometric evaluation in patients with asthma and major depressive disorder
The Quick Inventory of Depressive Symptomatology-Self-report: a psychometric evaluation in patients with asthma and major depressive disorder
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DOI：
10.1016/s1081-1206(10)60467-x
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发表时间：
2008-05-01
影响因子：
5.9
通讯作者：
Rush, A. John
中科院分区：
文献类型：
--
作者：
Brown, E. Sherwood;Murray, Michelle;Rush, A. John
背景：尽管抑郁和哮喘的发生率很高，但很少有研究提出评估哮喘患者抑郁症状严重程度的方法。目的：评估抑郁症状自评量表(QDS-SR16)的心理测量学特性，该量表由16个条目组成，方法：对73例非精神病性重度抑郁障碍的哮喘患者，在治疗结束时将QDS-SR16量表与30项抑郁症状自评量表(DS-SR30)和17项汉密尔顿抑郁量表(HRSD17)进行心理测量比较。结果：QDS-SR16量表在退出时具有较强的内部一致性(Cronbach alpha值分别为.87、0.95和0.87)。QDS-SR16总分与HRSD17总分高度相关(r=0.85)，QDS-SR16总分与IDS-SR30总分高度相关(r=0.97)。QDS-SR16各条目总分相关均显著(P<；.001)。QDS-SR16、IDS-SR30和HRSD17对症状变化的敏感度相当，表明三个量表均具有较高的同时效度。QDS-SR16基线到退出的变化总分与小型哮喘生活质量问卷呈显著负相关(r=-0.49，P<；.001)。结论：QDS-SR16量表具有良好的信度和结构效度。这一简短的自我报告格式的强大心理测量学特性及其对治疗变化的敏感性表明QDS-SR16是一种有价值的临床工具。
Background: Despite the high co-occurrence between depression and asthma, few studies have addressed methods assessing the severity of depressive symptoms among patients with asthma.Objective: To evaluate the psychometric properties of the Quick Inventory of Depressive Symptomatology-Self-report (QIDS-SR16), a 16-item measure of depressive symptom severity, in patients with asthma.Methods: The psychometric properties of the QIDS-SR16 were compared at treatment exit with those of the 30-item self-report Inventory of Depressive Symptomatology (IDS-SR30) and the 17-item clinician-rated Hamilton Rating Scale for Depression (HRSD17) in 73 outpatients with asthma who were treated with citaloprant or placebo for nonpsychotic major depressive disorder. Correlations between the depression rating scales and the Mini Asthma Quality of Life Questionnaire were calculated.Results: Internal consistency at exit was strong for the QIDS-SR16 (Cronbach alpha values are .87 for the QIDS-SR16, .95 for the IDS-SR30, and .87 for the HRSD17). The QIDS-SR16 and HRSD17 total scores were highly correlated (r = 0.85), as were the QIDS-SR16 and IDS-SR30 total scores (r = 0.97). All QIDS-SR16 item total score correlations were significant (P < .001). The QIDS-SR16, IDS-SR30, and HRSD17 showed comparable sensitivity to symptom change, indicating high concurrent validity for all 3 scales. The total QIDS-SR16 baseline to exit change score demonstrated a significant negative correlation (r = -0.49, P < .001) with the Mini Asthma Quality of Life Questionnaire. Thus, greater depressive symptom severity was associated with lower asthma-related quality of life.Conclusions: The QIDS-SR16 showed good reliability and impressive construct validity. Strong psychometric properties of this brief self-report format and its sensitivity to treatment change suggest that the QIDS-SR16 is a valuable clinical tool.