Effect of a companion dog on depression and anxiety levels of elderly residents in a long-term care facility
Effect of a companion dog on depression and anxiety levels of elderly residents in a long-term care facility
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DOI：
10.1111/j.1479-8301.2009.00268.x
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发表时间：
2009-03-01
期刊：
影响因子：
2
通讯作者：
Kemp, Rene
中科院分区：
文献类型：
--
作者：
Le Roux, Marieanna C.;Kemp, Rene
本研究的目的是评估衰老与阿尔茨海默病（AD）患者痴呆（BPSD）行为和心理症状之间的关系。符合条件的受试者是连续转诊的伴有BPSD的AD患者。根据试验时患者年龄，将AD患者组（n = 79，全AD组（WADG））分为两组：全AD组（WAD）中相对年长组（OG）（试验时年龄在81岁及以上，n = 40）和WAD中相对年轻组（YG）（试验时年龄在81岁以下，n = 39）。比较两组之间的人口统计数据（性别差异、教育水平和痴呆严重程度）、认知功能和BPSD。BPSD采用阿尔茨海默病行为病理学评定量表（behavior - ad）进行评估。在WADG、OG和YG中对BPSD进行因子分析。性别差异、文化程度、痴呆严重程度、认知功能无差异；而在昼夜节律方面，OG组的behavior - ad症状域总分显著高于YG组（学生t检验：P < 0.05）。因子分析表明，精神病是OG组的第一个因素，但在YG组中是第三个因素，并且OG组的精神病症状是由焦虑和恐惧引起的。从这些结果中，我们发现衰老对AD患者BPSD的影响表现为昼夜节律紊乱和精神错乱。
The aim of the present study was to evaluate the relationship between aging and the behavioral and psychological symptoms of dementia (BPSD) in patients with Alzheimer's disease (AD).Eligible subjects were consecutively referred AD patients with BPSD. According to patient age at the time of the test, the AD patient group (n = 79, whole AD group (WADG)) was divided into two groups: a relative older group (OG) in the whole AD group (WAD) (age at the time of test was 81 years or more, n = 40) and a relative younger group (YG) in the WAD (age at the time of test was below 81 years, n = 39). A comparison was made of the demographic data (sex difference, educational level and severity of dementia), cognitive functions and BPSD between the groups. BPSD was evaluated using the Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD). The factor analysis of BPSD was conducted in the WADG as well as in the OG and YG.Sex difference, educational level, severity of dementia and cognitive functions were not different; however, the total score of the BEHAVE-AD symptom domain in diurnal rhythm was significantly higher in the OG than in the YG (Student's t-test: P < 0.05). Factor analysis showed that psychosis was the first factor in the OG, but was the third factor in the YG and that the psychotic symptoms were caused by anxieties and phobias in the OG.From these results, we found that the effects of aging on the BPSD in AD were characterized by diurnal rhythm disturbance and psychosis.