Rapid Assembly of Functionalized Hydrodibenzofurans via Semipinacol Rearrangements.
Rapid Assembly of Functionalized Hydrodibenzofurans via Semipinacol Rearrangements.
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DOI：
10.1021/acs.orglett.5b02202
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发表时间：
2015-08
期刊：
影响因子：
5.2
通讯作者：
Xiaotong Yao;Xiaoni Xie;Chunyu Wang;L. Zu
中科院分区：
文献类型：
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作者：
Xiaotong Yao;Xiaoni Xie;Chunyu Wang;L. Zu
报道了一种通过史无前例的半片呐醇重排来合成功能化氢二苯并呋喃的独特策略。苯并呋喃-3-酮作为构造物的多种反应性使得简单的起始原料能够收敛地偶联，从而允许R基团的简单变化和构建具有稠环的氢二苯并呋喃。
A distinct strategy via unprecedented semipinacol rearrangements for the synthesis of functionalized hydrodibenzofurans is reported. The versatile reactivity of benzofuran-3-one as a building block enabled the convergent coupling of simple starting materials and, thus, allowed for the facile variation of R group and the construction of hydrodibenzofurans with fused rings.