Human auditory cortex is activated by omissions of auditory stimuli
Human auditory cortex is activated by omissions of auditory stimuli
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DOI：
10.1016/s0006-8993(96)01140-7
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发表时间：
1997-01-16
期刊：
影响因子：
2.9
通讯作者：
Hari, R
中科院分区：
文献类型：
--
作者：
Raij, T;McEvoy, L;Hari, R
9名健康成人使用全头122通道神经磁力仪记录了与罕见音调遗漏相关的皮质信号。刺激序列由单耳(左或右)50ms 1 kHz音调组成，每0.2或0.5个S重复一次，随机省略7%的音调。音调在颞叶上听皮层引起典型的反应。遗漏可在额叶和颞区引起强烈反应，与刺激侧无关，波幅峰值在145~195ms。当受试者没有注意到刺激时，反应幅度减弱了60%。遗漏反应起源于双侧颞上听觉皮质，表明听觉皮质在大脑对听觉环境时间特征的模拟中起着重要作用。在额叶后外侧皮质和颞叶上沟观察到额外的活动，右侧比左侧更常见。
Cortical signals associated with infrequent tone omissions were recorded from 9 healthy adults with a whole-head 122-channel neuromagnetometer. The stimulus sequence consisted of monaural (left or right) 50-ms 1-kHz tones repeated every 0.2 or 0.5 s, with 7% of the tones randomly omitted. Tones elicited typical responses in the supratemporal auditory cortices. Omissions evoked strong responses over temporal and frontal areas, independently of the side of stimulation, with peak amplitudes at 145-195 ms. Response amplitudes were 60% weaker when the subject was not attending to the stimuli. Omission responses originated in supratemporal auditory cortices bilaterally, indicating that auditory cortex plays an important role in the brain's modelling of temporal characteristics of the auditory environment. Additional activity was observed in the posterolateral frontal cortex and in the superior temporal sulcus, more often in the right than in the left hemisphere.