Outbreak of leptospirosis among triathlon participants in Germany, 2006
Outbreak of leptospirosis among triathlon participants in Germany, 2006
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DOI：
10.1186/1471-2334-10-91
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发表时间：
2010-04-10
影响因子：
3.7
通讯作者：
Jansen, Andreas
中科院分区：
文献类型：
--
作者：
Brockmann, Stefan;Piechotowski, Isolde;Jansen, Andreas
背景：2006年8月，一名运动员在海德堡附近和内卡河举行的铁人三项赛后发生钩端螺旋体病。为了研究可能的爆发，并确定感染的危险因素的流行病学调查performed.Methods：铁人三项的参与者通过电子邮件联系，并要求填写一份标准化的问卷。此外，他们亦被要求提供血清样本，以作细螺旋体病的化验诊断。确诊病例患者定义为临床病例（即发热和至少一种提示钩端螺旋体病的其他症状），至少有两种以下检测结果呈阳性：ELISA IgM、乳胶凝集试验或显微镜凝集试验。降雨量和温度records.Results：共142 507铁人三项运动员接触，其中，5个确诊钩端螺旋体病的情况下被发现。开放性伤口被确定为唯一的显着的患病风险因素（p = 0.02）。游泳比赛前的大雨可能增加了内卡河的钩端螺旋体污染。讨论：这是德国第一次爆发与竞技体育赛事有关的钩端螺旋体病。在与淡水接触的人群中，温带国家的卫生保健提供者也应考虑感染钩端螺旋体病的风险，特别是在大雨后的夏季。
Background: In August 2006, a case of leptospirosis occurred in an athlete after a triathlon held around Heidelberg and in the Neckar river. In order to study a possible outbreak and to determine risk factors for infection an epidemiological investigation was performed.Methods: Participants of the triathlon were contacted by e-mail and were asked to fill out a standardized questionnaire. In addition, they were asked to supply a serum sample for laboratory diagnosis of leptospirosis. A confirmed case patient was defined as a clinical case (i.e. fever and at least one additional symptom suggestive for leptospirosis) with at least two of the following tests positive: ELISA IgM, latex agglutination testing, or microscopic agglutination testing. Rainfall and temperature records were obtained.Results: A total of 142 of 507 triathletes were contacted; among these, five confirmed leptospirosis cases were found. Open wounds were identified as the only significant risk factor for illness (p = 0.02). Heavy rains that preceded the swimming event likely increased leptospiral contamination of the Neckar River.Discussion: This is the first outbreak of leptospirosis related to a competitive sports event in Germany. Among people with contact to freshwater, the risk of contracting leptospirosis should be considered by health care providers also in temperate countries, particularly in the summer after heavy rains.