A Novel Acoustic Evaluation Method for the Diagnosis of Adductor Spasmodic Dysphonia

A Novel Acoustic Evaluation Method for the Diagnosis of Adductor Spasmodic Dysphonia
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一种诊断内收肌痉挛性发声困难的新型声学评估方法

DOI:
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发表时间:
2023
影响因子:
1
通讯作者:
Jing Kang
Jing Kang
中科院分区:
医学4区
文献类型:
--
作者:
Boquan Liu;Mingjun Ji;Jin Fang;Qingyi Ren;Jinwei Lan;Zhixian Zhu;Pingjiang Ge;Jing Kang

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摘要 简介:内收肌痉挛性发声障碍(ADSD)的特点是喉部肌肉不自主痉挛。由于缺乏定量的评估方法,大多数测量方法在诊断 ADSD 时都表现出有效性和可靠性的困难。本研究旨在建立 ADSD 的新指标并确定其诊断效果。方法:我们调查了 49 名 ADSD 患者和 49 名健康参与者的 98 个声音样本。一个持续的元音被高清录音机记录下来。语音样本经过定期声学评估和新颖的全局维度(GD)方法。测量了两组的 GD、抖动、闪光、HNR、频移和 CPPS。结果:统计分析显示,GD 方法有效区分 ADSD 患者与健康参与者(p < 0.001,D'>0.8)。随后的多类接收器操作特性分析表明,与其他声学参数相比,GD 具有最显着的分类精度(曲线下面积 = 0.988)。结论:GD 是客观区分 ADSD 患者和健康参与者的有效指标。该指标可以帮助临床医生诊断 ADSD 患者。
Abstract Introduction: Adductor spasmodic dysphonia (ADSD) is characterized by involuntary laryngeal muscle spasms. Due to the lack of a quantitative evaluation method, most measurements have demonstrated difficulty in validity and reliability for diagnosing ADSD. This study aimed to establish a novel indicator for ADSD and determine its diagnostic effects. Methods: We investigated 98 voice samples from 49 patients with ADSD and 49 healthy participants. A sustained vowel was recorded by a high-definition audio recorder. Voice samples underwent regular acoustic evaluation and a novel global dimension (GD) method. GD, Jitter, Shimmer, HNR, Frequency shift, and CPPS were measured for both groups. Results: Statistical analysis revealed that the GD method effectively differentiated ADSD patients from healthy participants (p < 0.001, D′>0.8). Subsequent multiclass receiver operating characteristic analysis demonstrated that GD possessed the most significant classification accuracy (area under the curve = 0.988) compared with other acoustic parameters. Conclusion: GD was an effective metric for objective differentiation between ADSD patients and healthy participants. This metric could assist clinicians in the diagnosis of ADSD patients.
DOI: 10.1044/2021_jslhr-20-00429
发表时间: 2021-04
期刊: Journal of speech, language, and hearing research : JSLHR
影响因子: --
作者:
Boquan Liu;Hayley Raj;Logan Klein;Jack J. Jiang
通讯作者: Boquan Liu;Hayley Raj;Logan Klein;Jack J. Jiang