Manufacturing and characterization of 3-D hydroxyapatite bone tissue engineering scaffolds
Manufacturing and characterization of 3-D hydroxyapatite bone tissue engineering scaffolds
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DOI：
10.1111/j.1749-6632.2002.tb03061.x
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发表时间：
2002-01-01
期刊：
影响因子：
--
通讯作者：
Orton, DG
中科院分区：
文献类型：
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作者：
Chu, TMG;Hollister, SJ;Orton, DG
多孔羟基磷灰石（HA）植入体的内部结构直接影响其力学和生物学行为。然而，传统的加工方法在这方面提供的控制非常少。本文综述了一种新的加工技术，在我们的实验室制造支架与控制的内部架构。并对这些支架材料的力学性能和体内评价进行了初步研究。
Internal architecture has a direct impact on the mechanical and biological behaviors of porous hydroxyapatite (HA) implants. However, traditional processing methods provide very minimal control in this regard. This paper reviews a novel processing technique developed in our laboratory for fabricating scaffolds with controlled internal architectures. The preliminary mechanical property and in vivo evaluation of these scaffolds are also presented.