INFLUENCES OF CELL-VOLUME AND ADRENALECTOMY ON CATION FLUX IN DOG RED BLOOD-CELLS
INFLUENCES OF CELL-VOLUME AND ADRENALECTOMY ON CATION FLUX IN DOG RED BLOOD-CELLS
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DOI：
10.1016/0005-2736(76)90104-8
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发表时间：
1976-01-01
期刊：
影响因子：
--
通讯作者：
HOFFMAN, JF
中科院分区：
文献类型：
--
作者：
PARKER, JC;HOFFMAN, JF
Rates of 24Na and 42K entry into dog red blood cells were strongly influenced by cell volume. The kinetics of isotope movement were complex, and the cells were not in a steady state. By applying a simple, 2-compartment equation to the early time points, values for flux were calculated and corrected for the changes in surface/volume ratio which occurred when cells were shrunken or swollen. Curves were generated showing Na and K influx as functions of cell water content. A reinvestigation of the effects of adrenalectomy showed that all the observed changes in Na flux could be explained on the basis of alterations in red cell volume.
