Design and synthesis of biotinylated DHMEQ for direct identification of its target NF-kB components
Design and synthesis of biotinylated DHMEQ for direct identification of its target NF-kB components
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设计和合成生物素化 DHMEQ，用于直接鉴定其靶 NF-kB 成分
DOI：
10.1016/j.bmcl.2011.08.122
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
S.
中科院分区：
文献类型：
--
作者：
Saitoh;T.; Takeiri;M.; Gotoh;Y.; Ishikawa;Y.; Umezawa;K.; Nishiyama;S.
设计并合成了脱羟甲基氧奎诺米星(DHMEQ)衍生物，考察了其胞内靶点。合成的生物素探针具有膜通透性，并选择性地与靶蛋白P65结合。
The design and synthesis of dehydroxymethylepoxyquinomicin (DHMEQ) derivatives were carried out to investigate the intracellular targets. The synthetic biotin probe exhibited membrane permeability and combined selectively with the target protein p65.