Association Between Polycystic Ovary Syndrome and Risk of Pancreatic Cancer.
Association Between Polycystic Ovary Syndrome and Risk of Pancreatic Cancer.
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多囊卵巢综合症与胰腺癌风险之间的关联。
DOI：
10.1001/jamaoncol.2022.4540
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发表时间：
2022
期刊：
影响因子：
28.4
通讯作者：
Du,Mengmeng
中科院分区：
文献类型：
--
作者：
Peeri,NoahC;Landicino,MarcoV;Saldia,CAmethyst;Kurtz,RobertC;Rolston,VineetS;Du,Mengmeng
在目前的研究中，研究人员评估了446名患有胰腺腺癌的女性和209名没有个人癌症病史的女性的数据。胰腺癌患者在癌症诊断或入组时的平均年龄为63.8岁，对照组为57.7岁。每组中88%的患者是白人。糖尿病在病例中比对照组更常见（分别为26%和5%）。子宫切除术的比例相似（分别为22%和23%），卵巢切除术的比例相似（分别为19%和20%）。病例组和对照组的大多数患者都经历了更年期（分别为88%和78%），但少数患者在绝经后使用雌激素（分别为27%和37%）。
For the current study, researchers evaluated data from 446 women with pancreatic adenocarcinoma and 209 women with no personal history of cancer. 1 The mean age at cancer diagnosis or enrollment was 63.8 years among patients with pancreatic cancer and 57.7 years among control individuals. Eighty-eight percent of patients in each group were White.Diabetes was more common among cases than among control individuals (26% and 5%, respectively). Rates of hysterectomy were similar (22% and 23%, respectively), as were rates of oophorectomy (19% and 20%, respectively). A majority of patients in the case and control groups had undergone menopause (88% and 78%, respectively), but a minority had postmenopausal estrogen use (27% and 37%, respectively).