Lymphedema: separating fact from fiction.
Lymphedema: separating fact from fiction.
复制标题
淋巴水肿：区分事实与虚构。
作者：
S. Mclaughlin
淋巴水肿是癌症治疗的一种令人担忧的并发症，对生存率有负面影响。乳腺癌相关性水肿的发生率范围为6%至70%，但水肿可能是一种常见且报告不足的发病率。没有诊断和评估的标准指南。虽然水肿的真正病因尚不清楚，但放疗、化疗、乳房手术类型和腋窝手术范围是常见的危险因素。然而，切除的淋巴结数量与水肿风险之间的关系并不明显。临床试验的重点是如何减少腋窝淋巴结清扫的需要，即使是在前哨淋巴结阳性的情况下，以帮助减少腋窝发病率。降低风险的做法，包括避免皮肤穿刺和同侧上肢的血压，以及预防行为，如在航空旅行期间穿着压缩服装，继续受到医疗和幸存者社区的倡导，尽管缺乏严格的证据支持其益处。新出现的数据支持运动的风险和受影响的妇女与水肿时，开始逐渐增加谨慎。
Lymphedema is a feared complication of cancer treatment and one that negatively impacts survivorship. The incidence of breast cancer-related lymphedema ranges from 6% to 70%, but lymphedema may be a common and under-reported morbidity. No standard guidelines for its diagnosis and assessment exist. Although the true etiology of lymphedema remains unknown, radiation, chemotherapy, type of breast surgery, and extent of axillary surgery are commonly cited risk factors. However, the relationship between the number of nodes removed and the risk of lymphedema is not clearly correlated. Clinical trials are focusing on ways to reduce the need for axillary dissection even in the setting of a positive sentinel node, to help minimize axillary morbidity. Risk-reduction practices, including avoidance of skin puncture and blood pressures in the ipsilateral upper extremity, and precautionary behaviors such as wearing compression garments during air travel continue to be advocated by the medical and survivor communities, despite a lack of rigorous evidence supporting their benefit. Emerging data support exercise in at-risk and affected women with lymphedema when started gradually and increased cautiously.
影响因子：
45.3
作者：
McLaughlin, Sarah A.;Wright, Mary J.;Van Zee, Kimberly J.
通讯作者：
Van Zee, Kimberly J.
DOI：
10.1001/jama.2011.90
发表时间：
2011-02-09
期刊：
JAMA
影响因子：
--
作者：
Giuliano AE;Hunt KK;Ballman KV;Beitsch PD;Whitworth PW;Blumencranz PW;Leitch AM;Saha S;McCall LM;Morrow M
通讯作者：
Morrow M