Cognitive impairment in chronic kidney disease: keep vascular disease in mind.

Cognitive impairment in chronic kidney disease: keep vascular disease in mind.
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DOI:
10.1038/ki.2013.437
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发表时间:
2014-03
影响因子:
19.6
通讯作者:
--
中科院分区:
医学1区
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--
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认知障碍是慢性肾脏病(CKD)患者发病的主要原因,与生活质量降低、更难坚持用药和生存率降低有关。先前的数据表明CKD患者的血管疾病和认知障碍之间存在关系,尽管对总体风险因素仍知之甚少。至关重要的是,临床医生应该意识到在CKD的所有阶段发生的认知障碍的高发生率,尽管有时很微妙,但可能会影响这些个体的理解和决策,并可能预示着未来更衰弱的障碍。
Cognitive impairment is a major cause of morbidity in people with chronic kidney disease (CKD) and is associated with lower quality of life, more difficulty adhering to medications, and worse survival. Prior data suggest a relationship between vascular disease and cognitive impairment in individuals with CKD, although overall risk factors remain poorly understood. Critically, clinicians should be aware of the high rates of cognitive impairment that occur in all stages of CKD, which, although sometimes subtle, may impact comprehension and decision making in these individuals and may herald future, more debilitating impairment.
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