特集 小脳と大脳-Masao Itoのレガシー 小脳神経回路の生後発達

特集 小脳と大脳-Masao Itoのレガシー 小脳神経回路の生後発達
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特色小脑和大脑 - Masao Ito 的小脑神经回路产后发育遗产

DOI:
10.11477/mf.1416201457
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发表时间:
2019
期刊:
影响因子:
--
通讯作者:
Kano M
Kano M
中科院分区:
--
文献类型:
--
作者:
Watanabe T;Suzuki H;Kano M

文献摘要

相似文献

伊藤正雄教授在阐明小脑神经元回路的结构和功能方面做出了巨大贡献。他提出了小脑运动学习理论和内部模型假说,并探讨了复杂的小脑功能是如何从神经回路的运作中产生的。在本文中,我们首先简要介绍了小脑神经回路的主要细胞类型和突触组织。然后我们介绍了在出生后发育过程中,成熟的小脑神经回路是如何通过突触的形成和修剪形成的。我们也提到在出生后发育过程中抑制性神经元和神经胶质细胞的成熟。
Prof. Masao Ito contributed greatly to the elucidation of the structure and function of cerebellar neuronal circuits. He formulated a cerebellar motor learning theory and an internal model hypothesis and pursued how complex cerebellar functions resulted from the operation of neural circuits. In this article, we first provide a brief overview of the major cell types and the synaptic organization of cerebellar neural circuits. Then we introduce how mature cerebellar neural circuits are shaped through synapse formation and pruning during postnatal development. We also refer to the maturation of inhibitory neurons and glial cells during postnatal development.