Polysiloxane cationic biocides with imidazolium salt (ImS) groups, synthesis and antibacterial properties
Polysiloxane cationic biocides with imidazolium salt (ImS) groups, synthesis and antibacterial properties
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DOI：
10.1016/j.eurpolymj.2008.11.045
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发表时间：
2009-03
影响因子：
6
通讯作者：
U. Mizerska;W. Fortuniak;J. Chojnowski;R. Hałasa;A. Konopacka;W. Werel
中科院分区：
文献类型：
--
作者：
U. Mizerska;W. Fortuniak;J. Chojnowski;R. Hałasa;A. Konopacka;W. Werel
合成了新型含N，N′-二烷基咪唑盐（ImS）侧基的聚硅氧烷，并与传统的含季铵盐（QAS）侧基的聚硅氧烷进行了比较。在相同的条件下，在水溶液中测试和比较这些聚合物对两种常见的革兰氏阳性细菌菌株和三种革兰氏阴性细菌菌株的抑菌能力。这些新的含ImS的聚合物对所有研究的细菌表现出高的抗菌效力，类似于用QAS基团取代的那些。咪唑鎓取代的聚硅氧烷的优点源于其与烷基季铵官能化聚合物相比更高的热稳定性，如通过热重研究所证明的。
Novel polysiloxanes with pendant biocidal N,N′-dialkylimidazolium salt (ImS) groups were synthesized and compared with polysiloxanes bearing conventional biocidal quaternary ammonium salt (QAS) groups. The bacteriostatic power of these polymers was tested and compared under the same conditions in aqueous solution against two common strains of Gram positive bacteria and three strains of Gram negative bacteria. These new ImS containing polymers exhibited high antibacterial potency against all bacteria studied, similar to those substituted with QAS groups. The advantage of the imidazolium substituted polysiloxane stems from its higher thermal stability, as compared with the quaternary alkylammonium functionalized polymer, as demonstrated by thermogravimetric studies.