A saccharides sensor developed by symmetrical optical waveguide-based surface plasmon resonance

A saccharides sensor developed by symmetrical optical waveguide-based surface plasmon resonance
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DOI:
10.1142/s1793545815500030
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发表时间:
2015-03
影响因子:
2.5
通讯作者:
Ang Li;Zhouyi Guo;Qing Peng;Chan Du;Xida Han;Le Liu;Jun Guo;Yonghong He;Y. Ji
Ang Li;Zhouyi Guo;Qing Peng;Chan Du;Xida Han;Le Liu;Jun Guo;Yonghong He;Y. Ji
中科院分区:
医学3区
文献类型:
--
作者:
Ang Li;Zhouyi Guo;Qing Peng;Chan Du;Xida Han;Le Liu;Jun Guo;Yonghong He;Y. Ji

文献摘要

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提出了一种基于对称光波导(SOW)的表面等离子体共振(SPR)技术的新型光纤传感器。这种独特的MgF 2/Au/MgF 2/Analyte膜结构导致更长的表面等离子体波(SPW)传播长度和深度,从而导致分辨率的增加。在本文中,我们设法装饰的介电界面(MgF 2层)通过沉积一个薄的聚多巴胺膜作为表面粘附,提供了一个平台,与探针分子的二次反应。3-选择氨基苯硼酸(3-PBA)作为探针分子。对血糖正常的糖尿病和白内障患者的房水进行了分析,结果表明该传感器在血糖监测方面具有很大的潜力,可以应用于未来的生物监测领域。
We proposed a new saccharides sensor developed by symmetrical optical waveguide (SOW)-based surface plasmon resonance (SPR). This unique MgF2/Au/MgF2/Analyte film structure results in longer surface plasmon wave (SPW) propagation lengths and depths, leading to an increment of resolution. In this paper, we managed to decorate the dielectric interface (MgF2 layer) by depositing a thin polydopamine film as surface-adherent that provides a platform for secondary reactions with the probe molecule. 3-Aminophenylboronic acid (3-PBA) is chosen to be the saccharides sense probe molecule in the present work. The aqueous humor of Diabetes and Cataract patient whose blood glucose level is normal are analyzed and the results demonstrated that this sensor shows great potential in monitoring the blood sugar and can be adapted in the field of biological monitoring in the future.