Salivary microbial levels in relation to periodontal status and caries development
Salivary microbial levels in relation to periodontal status and caries development
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DOI：
10.1111/j.1600-0765.2009.01213.x
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发表时间：
2010-04-01
影响因子：
3.5
通讯作者：
Ito, K.
中科院分区：
文献类型：
--
作者：
Iwano, Y.;Sugano, N.;Ito, K.
背景与目的：虽然龋病与牙周病呈负相关，但已有研究报道龋齿、缺牙、充填牙指数与牙周病呈正相关。本研究旨在探讨龋病与牙周病的关系。材料与方法：采用实时定量聚合酶链式反应技术，对40例不同程度的龋病和牙周病患者的临床参数和唾液中变形链球菌进行检测。结果：牙周健康组唾液中变形链球菌水平明显高于牙周炎组。无龋组的唾液中牙龈假单胞菌水平显著高于有龋齿的牙周健康组。经过牙周治疗后，唾液中变形链球菌的水平明显升高。结论：从临床和细菌学的角度来看，牙周炎与龋病之间存在负相关关系。
Background and Objective:Although an inverse relationship between caries and periodontal disease has been suggested, some studies have reported a positive correlation between periodontal disease and the decayed, missing and filled teeth (DMF) index. The aim of the present study was to examine the relationship between caries and periodontal disease.Material and Methods:We assessed the clinical parameters and salivary levels of Porphyromonas gingivalis and Streptococcus mutans using real-time polymerase chain reaction in 40 subjects with varying degrees of caries and periodontal disease.Results:The salivary levels of S. mutans were significantly higher in the periodontally healthy group than in the periodontitis group. The salivary levels of P. gingivalis were significantly higher in the caries-free group than in the periodontally healthy group with caries. The salivary levels of S. mutans were significantly increased after the initial periodontal treatment.Conclusions:This study showed that an inverse relationship exists between periodontitis and caries in terms of the clinical and bacteriological findings.