Deoxygenative Borylation of Secondary and Tertiary Alcohols
Deoxygenative Borylation of Secondary and Tertiary Alcohols
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DOI：
10.1002/anie.201904028
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发表时间：
2019-07-08
影响因子：
16.6
通讯作者：
Studer, Armido
中科院分区：
文献类型：
--
作者：
Friese, Florian W.;Studer, Armido
介绍了仲醇和叔醇的脱氧自由基硼化反应的两种不同方法。这些转化要么通过无金属硅基自由基介导的途径进行，要么利用可见光光氧化还原催化。容易获得的黄原酸盐或草酸甲酯被用作自由基前体物。该反应具有底物范围广、官能团耐受性高、反应条件温和、实用等特点。
Two different approaches for the deoxygenative radical borylation of secondary and tertiary alcohols are presented. These transformations either proceed through a metal-free silyl-radical-mediated pathway or utilize visible-light photoredox catalysis. Readily available xanthates or methyl oxalates are used as radical precursors. The reactions show broad substrate scope and high functional-group tolerance, and are conducted under mild and practical conditions.