Interventions Transformed Through Technology to Improve Cognitive Function in Heart Failure.
Interventions Transformed Through Technology to Improve Cognitive Function in Heart Failure.
复制标题
通过技术转变干预措施以改善心力衰竭的认知功能。
DOI：
10.1097/jcn.0000000000000609
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Haedtke,Christine
中科院分区：
文献类型：
--
作者：
Pressler,SusanJ;Jung,Miyeon;Haedtke,Christine
Cognitive function is essential to well-being and survival. Among patients with heart failure (HF), cognitive dysfunction was an independent predictor of 12-month all-cause mortality. 1 The cognitive domains most often impaired in HF are memory, attention, working memory, processing speed, and executive function. 2–7 In past studies, 23% to 50% of patients had memory dysfunction2, 3 and 15% to 27% had attention dysfunction. 4, 5 Memory and attention are foundational cognitive processes that support the other cognitive functions (eg, executive function). 8 The most likely etiologies of cognitive dysfunction in HF are cerebral hypoperfusion9 resulting from decreased cardiac output and cerebral microemboli. 10 Alterations in brain structure and functional connectivity have been identified in the hippocampus, frontal, and prefrontal cortex among patients with HF, 11, 12 and these alterations are consistent with the cognitive domains impaired. The prevalence of cognitive dysfunction in HF and its association with higher mortality support the urgent need for development and testing of novel interventions that are designed to improve cognitive function and slow cognitive decline. The ideal intervention would meet the following 5 criteria:(1) guided by scientific principles,(2) targeted to specific cognitive domains,(3) tailored to individual cognitive performance levels,(4) deliverable in the home setting to minimize patient and family caregiver burden, and (5) scalable at relatively low cost for delivery to large numbers of patients. Computerized cognitive training and natural restorative environment intervention are guided by scientific principles and have been transformed through technology over time to meet the remaining 4 criteria. The interventions are being tested for efficacy among patients with HF.
Cognitive function is essential to well-being and survival. Among patients with heart failure (HF), cognitive dysfunction was an independent predictor of 12-month all-cause mortality. 1 The cognitive domains most often impaired in HF are memory, attention, working memory, processing speed, and executive function. 2–7 In past studies, 23% to 50% of patients had memory dysfunction2, 3 and 15% to 27% had attention dysfunction. 4, 5 Memory and attention are foundational cognitive processes that support the other cognitive functions (eg, executive function). 8 The most likely etiologies of cognitive dysfunction in HF are cerebral hypoperfusion9 resulting from decreased cardiac output and cerebral microemboli. 10 Alterations in brain structure and functional connectivity have been identified in the hippocampus, frontal, and prefrontal cortex among patients with HF, 11, 12 and these alterations are consistent with the cognitive domains impaired. The prevalence of cognitive dysfunction in HF and its association with higher mortality support the urgent need for development and testing of novel interventions that are designed to improve cognitive function and slow cognitive decline. The ideal intervention would meet the following 5 criteria:(1) guided by scientific principles,(2) targeted to specific cognitive domains,(3) tailored to individual cognitive performance levels,(4) deliverable in the home setting to minimize patient and family caregiver burden, and (5) scalable at relatively low cost for delivery to large numbers of patients. Computerized cognitive training and natural restorative environment intervention are guided by scientific principles and have been transformed through technology over time to meet the remaining 4 criteria. The interventions are being tested for efficacy among patients with HF.
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DOI：
10.1053/hl.1999.v28.a101053
发表时间：
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期刊：
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影响因子：
--
作者：
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