Dietary potassium intake is beneficial to bone health in a low calcium intake population: the Korean National Health and Nutrition Examination Survey (KNHANES) (2008-2011)

Dietary potassium intake is beneficial to bone health in a low calcium intake population: the Korean National Health and Nutrition Examination Survey (KNHANES) (2008-2011)
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DOI:
10.1007/s00198-017-3908-4
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发表时间:
2017-05-01
影响因子:
4
通讯作者:
Shin, C. S.
Shin, C. S.
中科院分区:
医学2区
文献类型:
--
作者:
Kong, S. H.;Kim, J. H.;Shin, C. S.

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膳食钾可以中和酸负荷,减少骨钙流失,从而对骨矿物质密度产生有益影响。在这项全国性的韩国人口研究中,饮食中钾的摄入量与老年男性和绝经后女性骨密度的改善有关。营养是影响骨骼健康的主要可变因素。膳食钾中伴随的阴离子可作为碱性来源,中和酸负荷并减少骨中的钙流失。我们的目的是评估膳食钾摄入量和骨矿物质密度(BMD)之间的关联在韩国population.We分析了3135名男性年龄> 50岁和4052绝经后妇女从韩国国家健康和营养检查调查(KNHANES)。采用双能X线骨密度仪测量腰椎、全髋和股骨颈BMD。每日食物摄入量采用食物频率问卷进行评估,当我们根据钾摄入量将参与者分为三分位时,最高钾摄入量三分位组显示出比低钾摄入量三分位组显著更高的全髋关节和股骨颈BMD(三分位数为0.914 +/- 0.004、0.928 +/- 0.003、0.925 +/- 0.004 mg/天,全髋关节P = 0.014;股骨颈为0.736 +/- 0.003、0.748 +/- 0.003、0.750 +/- 0.004 mg/天,P = 0.012)。钾摄入量最高的三分位数组绝经后妇女的腰椎、全髋和股骨颈BMD显著高于钾摄入量较低的三分位数组(0.793 +/- 0.004,0.793 +/- 0.003,0.805 +/- 0.004 mg/天,腰椎P = 0.029;全髋关节0.766 +/- 0.003、0.770 +/- 0.002、0.780 +/- 0.003 mg/天,P = 0.002; 0.615 +/- 0.003,0.619 +/- 0.002,0.628 +/- 0.003 mg/天,股骨颈P = 0.002)。在年龄> 50岁的男性和绝经后女性中,膳食钾摄入量与BMD呈正相关,表明膳食钾摄入量对骨骼健康的有益作用。
Dietary potassium may neutralize acid load and reduce calcium loss from the bone, leading to beneficial effect on bone mineral density. In this nationwide Korean population study, dietary potassium intake was associated with improved bone mineral density in older men and postmenopausal women.Nutrition is a major modifiable factor that affects bone health. The accompanying anion in dietary potassium may act as an alkaline source by neutralizing the acid load and reducing calcium loss from the bone. We aimed to evaluate the association between dietary potassium intake and bone mineral density (BMD) in the Korean population.We analyzed a total of 3135 men aged > 50 years and 4052 postmenopausal women from the Korean National Health and Nutrition Examination Survey (KNHANES). Lumbar spine, total hip, and femur neck BMD were measured using dual energy X-ray absorptiometry. The daily food intake was assessed using a food frequency questionnaire.When we divided the participants into tertiles based on the intake of potassium intake, the highest potassium intake tertile group showed a significantly higher total hip and femur neck BMD as compared to lower tertile groups (0.914 +/- 0.004, 0.928 +/- 0.003, 0.925 +/- 0.004 mg/day across the tertiles, P = .014 for total hip; 0.736 +/- 0.003, 0.748 +/- 0.003, 0.750 +/- 0.004 mg/day, P = .012 for femur neck). Postmenopausal women in the highest potassium intake tertile group showed significantly higher lumbar, total hip, and femur neck BMD as compared to those in lower potassium intake tertile groups (0.793 +/- 0.004, 0.793 +/- 0.003, 0.805 +/- 0.004 mg/day across the tertiles, P = .029 for lumbar spine; 0.766 +/- 0.003, 0.770 +/- 0.002, 0.780 +/- 0.003 mg/day, P = .002 for total hip; 0.615 +/- 0.003, 0.619 +/- 0.002, 0.628 +/- 0.003 mg/day, P = .002 for femur neck).Dietary potassium intake was positively associated with BMD in men aged > 50 years and postmenopausal women, indicating the beneficial effects of dietary potassium intake on bone health.