Understanding Prostate Cancer in Gay, Bisexual, and Other Men Who Have Sex with Men and Transgender Women: A Review of the Literature
Understanding Prostate Cancer in Gay, Bisexual, and Other Men Who Have Sex with Men and Transgender Women: A Review of the Literature
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DOI：
10.1007/s11930-019-00234-7
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发表时间：
2019-12-01
影响因子：
2
通讯作者：
West, William
中科院分区：
文献类型：
--
作者：
Rosser, B. R. Simon;Hunt, Shanda L.;West, William
性和性别少数群体的前列腺癌是一个新兴的医疗和公共卫生问题。本综述的目的是总结同性恋、双性恋和其他男男性行为者（GBM）和跨性别女性（TGW）前列腺癌的科学状况。我们对截至2017年2月有关该主题的所有出版物进行了文献综述。有88篇独特的论文（83篇关于GBM中的前列腺癌和5篇TGW中的前列腺癌病例报告），出现了一个小而强大的文献。这篇评论的前半部分批评了迄今为止的文献，确定了研究方法的差距。第二部分总结了11个领域的主要调查结果。鉴于这一公认的有限文献，GBM似乎比其他男性更少筛查前列腺癌，但他们被诊断患有前列腺癌的比率大致相同。与其他男性相比，GBM的泌尿、肠道和整体生活质量较差，但治疗后的性生活质量较好;所有这些发现都需要更多的研究。TGW中的前列腺癌仍然很罕见，研究不足，因为文献仅限于单个病例的临床报告。
Prostate cancer in sexual and gender minorities is an emerging medical and public health concern. The purpose of this review is to summarize the state of the science on prostate cancer in gay, bisexual, and other men who have sex with men (GBM) and transgender women (TGW). We undertook a literature review of all publications on this topic through February 2017. With 88 unique papers (83 on prostate cancer in GBM and five case reports of prostate cancer in TGW), a small but robust literature has emerged. The first half of this review critiques the literature to date, identifying gaps in approaches to study. The second half summarizes the key findings in eleven areas. In light of this admittedly limited literature, GBM appears to be screened for prostate cancer less than other men, but they are diagnosed with prostate cancer at about the same rate. Compared to other men, GBM have poorer urinary, bowel, and overall quality-of-life outcomes but better sexual outcomes after treatment; all these findings need more research. Prostate cancer in TGW remains rare and under researched, as the literature is limited to single-case clinical reports.