Anatomy, Thorax, Heart Muscles
Anatomy, Thorax, Heart Muscles
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解剖学、胸部、心肌
DOI：
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发表时间：
2019
期刊：
影响因子：
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通讯作者：
N. Mahabadi
中科院分区：
文献类型：
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作者：
Dan B. Tran;N. Mahabadi
心肌排列在心肌或心脏壁的中间层上，并且负责心脏泵的收缩功能。心肌由心肌细胞组成，具有独特的细胞和生理特征，使其能够产生力量以维持整个身体的足够组织和器官灌注。心肌是最早起作用的胚胎器官之一，它在一生中不断收缩和跳动。心肌细胞由冠状动脉血管系统、心脏血管系统和自主神经支配的复杂系统供应，排列在心脏每个腔室的最厚层。心血管疾病是全世界死亡的主要原因。这些疾病中的大量涉及具有不同病理生理学机制的心肌，导致收缩功能障碍、细胞损伤和死亡以及心脏泵衰竭。然而，许多干预措施，治疗方案和疗法旨在最大限度地减少损害，恢复功能，预防发生并降低心血管疾病的风险。
The heart muscles line the myocardium, or middle layer of the heart walls, and are responsible for the contractile function of the cardiac pump. Composed of cardiomyocytes, the heart muscle has distinctive cellular and physiological features allowing it to generate force to maintain adequate tissue and organ perfusion throughout the entire body. Heart muscle makes up one of the earliest functioning embryonic organs that continues to contract and beat from development throughout a lifetime. Supplied by a complex system of coronary vasculature, cardiac lymphatics, and autonomic innervation, cardiomyocytes line the thickest layer of every chamber of the heart. Cardiovascular diseases are the leading cause of mortality worldwide. A vast number of these diseases involve the heart muscles with diverse mechanisms of pathophysiology, leading to contractile dysfunction, cell damage and death, and cardiac pump failure. However, numerous interventions, treatment options, and therapies are aimed at minimizing damage, restoring functionality, preventing the occurrence, and reducing the risk of cardiovascular disease.