INTEGRATED CLINICAL EVALUATION OF TYPE 2A IDIOPATHIC JUXTAFOVEOLAR RETINAL TELANGIECTASIS
INTEGRATED CLINICAL EVALUATION OF TYPE 2A IDIOPATHIC JUXTAFOVEOLAR RETINAL TELANGIECTASIS
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DOI：
10.1097/iae.0b013e3181b9f11e
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发表时间：
2010-02-01
影响因子：
3.3
通讯作者：
Staurenghi, Giovanni
中科院分区：
文献类型：
--
作者：
Bottoni, Ferdinando;Eandi, Chiara M.;Staurenghi, Giovanni
目的：描述光谱高分辨率光学相干断层扫描（OCT）的结果与眼底自发荧光（FAF），共焦蓝光反射（CBR），荧光素血管造影（FA）模式的患者受影响的2A型特发性juxfoveolar视网膜毛细血管扩张症。方法：我们回顾了OCT，FA，CBR，和FAF图像的双眼从11例受影响的2A型特发性juxfoveolar视网膜毛细血管扩张症。1只眼睛患有2期疾病，13只眼睛患有3期疾病，5只眼睛患有4期疾病，3只眼睛患有5期疾病。所有的成像模式获得了与共焦扫描激光检眼镜和光谱域OCT的组合仪器。同时收购的OCT图像与FA，CBR，和FAF图像实现了完美的点到点correspondence.Results：增加旁的CBR观察到所有，但2只眼睛，有第5阶段的疾病。对应的FAF和视网膜内囊肿的解剖定位观察在16只眼睛的囊肿是可见的OCT。所有的眼睛都表现出一些改变的丛状层。在4只病灶性和椭圆形CBR模式的眼睛中，CBR增加和晚期FA高荧光之间存在对应关系，而10只环形病变的眼睛中没有这种对应关系。CBR增加的模式对应于94%合格眼睛中FAF增加的区域。结论：具有点对点相关性的光谱域OCT和参考图像（FA、FAF和CBR）的同时采集可进一步增加对2A型特发性近中心凹视网膜毛细血管扩张中形态学改变的理解。RETINA 30：317-326，2010
Purpose: To describe spectral high-resolution optical coherence tomography (OCT) findings correlated with fundus autofluorescence (FAF), confocal blue reflectance (CBR), and fluorescein angiography (FA) patterns in patients affected by Type 2A idiopathic juxtafoveolar retinal telangiectasis.Methods: We reviewed OCT, FA, CBR, and FAF images of both eyes from 11 patients affected by Type 2A idiopathic juxtafoveolar retinal telangiectasis. One eye had Stage 2 disease, 13 eyes had Stage 3 disease, 5 eyes had Stage 4 disease, and 3 eyes had Stage 5 disease. All the imaging modalities were obtained with a combined instrument for confocal scanning laser ophthalmoscopy and Spectral-domain OCT. Simultaneous acquisition of OCT images with FA, CBR, and FAF images was achieved with perfect point-to-point correspondence.Results: Increased parafoveal CBR was observed in all but 2 eyes that had Stage 5 disease. A correspondence of hyperautofluorescence on FAF and anatomical localization of the intraretinal cyst was observed in the 16 eyes where the cyst was visible by OCT. All eyes showed some alterations of the plexiform layers. A correspondence between increased CBR and late-phase FA hyperfluorescence occurred in the 4 eyes with focal and oval CBR pattern, whereas none of the 10 eyes with ring-pattern lesions had this correspondence. Patterns of increased CBR corresponded to areas of increased FAF in 94% of eligible eyes.Conclusion: The simultaneous acquisition of Spectral-domain OCT and reference images (FA, FAF, and CBR) with point-to-point correlation may further add to the understanding of morphologic alterations in Type 2A idiopathic juxtafoveolar retinal telangiectasis.RETINA 30: 317-326, 2010