Movement Intention After Parietal Cortex Stimulation in Humans
Movement Intention After Parietal Cortex Stimulation in Humans
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DOI：
10.1126/science.1169896
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发表时间：
2009-05-08
期刊：
影响因子：
56.9
通讯作者：
Sirigu, Angela
中科院分区：
文献类型：
--
作者：
Desmurget, Michel;Reilly, Karen T.;Sirigu, Angela
顶叶和运动前皮质区域是运动意图和运动反应被意识到的有力竞争者。我们在7名接受清醒脑部手术的患者中使用了电刺激。刺激右侧顶下区域会激发强烈的移动对侧手、手臂或脚的意图和欲望，而刺激左侧顶下区域则会激发移动嘴唇和说话的意图。当顶区的刺激强度增加时，参与者认为他们真的做了这些动作，尽管没有检测到肌电活动。刺激运动前区域引发了明显的口腔和对侧肢体运动。然而，患者坚决否认他们搬家了。因此，有意识的意图和运动意识源于动作执行前顶叶活动的增加。
Parietal and premotor cortex regions are serious contenders for bringing motor intentions and motor responses into awareness. We used electrical stimulation in seven patients undergoing awake brain surgery. Stimulating the right inferior parietal regions triggered a strong intention and desire to move the contralateral hand, arm, or foot, whereas stimulating the left inferior parietal region provoked the intention to move the lips and to talk. When stimulation intensity was increased in parietal areas, participants believed they had really performed these movements, although no electromyographic activity was detected. Stimulation of the premotor region triggered overt mouth and contralateral limb movements. Yet, patients firmly denied that they had moved. Conscious intention and motor awareness thus arise from increased parietal activity before movement execution.