Children's reading performance is correlated with white matter structure measured by diffusion tensor imaging
Children's reading performance is correlated with white matter structure measured by diffusion tensor imaging
复制标题
DOI：
10.1016/s0010-9452(08)70272-7
复制
发表时间：
2005-06-01
期刊：
影响因子：
3.6
通讯作者：
Wandell, B
中科院分区：
文献类型：
--
作者：
Deutsch, GK;Dougherty, RF;Wandell, B
我们使用扩散张量成像(DTI)，一种磁共振成像的形式，研究了具有广泛阅读能力水平的儿童(n=14)的脑白质结构。在阅读能力正常的儿童和阅读能力差的儿童之间，先前被描述为与成年读者的阅读能力相同的左侧颞顶区的白质结构也有所不同。具体地说，使用分数各向异性(FA)和连贯指数(CI)测量的白质结构与阅读、拼写和快速命名成绩的行为测量显著相关。一般来说，较低的各向异性和较低的一致性与较低的表现分数相关。尽管儿童的差异比成人的小，但研究结果支持这样一种假设，即左侧顶叶神经通路的结构是发展流利阅读所需的神经系统的重要组成部分。
We investigated the white matter structure in children (n = 14) with a wide range of reading performance levels using diffusion tensor imaging (DTI), a form of magnetic resonance imaging. White matter structure in a left temporo-parietal region that had been previously described as covarying with reading skill in adult readers also differs between children who are normal and poor readers. Specifically, the white matter structure measured using fractional anisotropy (FA) and coherence index (CI) significantly correlated with behavioral measurements of reading, spelling, and rapid naming performance. In general, lower anisotropy and lower coherence were associated with lower performance scores. Although the magnitude of the differences in children are smaller than those in adults, the results support the hypothesis that the structure of left temporoparietal neural pathways is a significant component of the neural system needed to develop fluent reading.