Spinal cord functional anatomy.
Spinal cord functional anatomy.
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DOI：
10.1212/01.con.0000461082.25876.4a
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发表时间：
2015-02-01
期刊：
影响因子：
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通讯作者：
Cho, Tracey A
中科院分区：
文献类型：
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作者：
Cho, Tracey A
综述的目的：本文回顾了脊髓白质通路和灰质柱的神经解剖学安排，并探讨了脊髓损伤如何根据损伤的横断面和纵向程度导致典型的症状和体征。研究结果：由于改进的成像技术和新的生物标记物有助于更容易地识别脊髓疾病，熟悉经典的脊髓综合征和定位原则对于及时认识脊髓受累和有效的诊断测试仍然是至关重要的，以指导治疗和避免永久性损伤。了解这些通路和细胞柱的组织，以及它们周围的结构和血液供应，使临床医生能够定位脊柱内的突起。这反过来可以提示所涉及的病理过程的类型，并指导进一步的评估和处理。
PURPOSE OF REVIEW: This article reviews the neuroanatomical arrangement of the white matter pathways and gray matter columns of the spinal cord and explores how injury to the spinal cord leads to a typical constellation of symptoms and signs depending on the cross-sectional and longitudinal extent of the lesion.RECENT FINDINGS: As refined imaging techniques and novel biomarkers help identify spinal cord diseases more readily, familiarity with the classic spinal cord syndromes and localizing principles remains essential for prompt recognition of spinal cord involvement and efficient diagnostic testing in order to direct therapy and avoid permanent injury.SUMMARY: Spinal cord disease can progress rapidly and cause debilitating deficits, making prompt recognition and treatment crucial. Knowledge of the organization of these pathways and cell columns, along with their surrounding structures and blood supply, allows the clinician to localize processes within the spinal column. This, in turn, can suggest the type of pathologic process involved and direct further evaluation and management.