Solid‐Liquid Extraction of Taxane Compounds from Yew Needle
Solid‐Liquid Extraction of Taxane Compounds from Yew Needle
复制标题
红豆杉针中紫杉烷类化合物的固液萃取
DOI：
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
Yoshinobu Morita
中科院分区：
文献类型：
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作者：
J. Kawasaki;H. Kosuge;H. Habaki;Yoshinobu Morita
摘要用甲醇固液萃取红豆杉针叶中的紫杉烷类化合物。萃取液中各组分的浓度是根据萃取物中的观察浓度和物质平衡方程以及溶剂渗透模型估算出来的。得到的分配系数与颗粒大小无关。这表明萃取物可能与萃余液中的液体溶液处于平衡状态。在实验结果的基础上，采用理想级数计算，研究了操作条件对逆流-多级萃取分离性能的影响。
Abstract Solid‐liquid extraction of the taxane compounds in yew needles is carried out with methanol. The concentration of each component in the raffinate is estimated from the observed concentration in the extract and material balance equations with a solvent‐permeation model that solvent permeates the solid. The obtained distribution coefficient is found to be independent of the particle size. It suggests a possibility that the extract is in equilibrium with the liquid solution in the raffinate. Based on the experimental results, the effect of operating conditions on separation performance of countercurrent‐multistage extraction is studied by using the ideal stage calculation.
影响因子：
2.9
作者：
He, LF;Jagtap, PGF;Horwitz, SB
通讯作者：
Horwitz, SB