Time-dependent ultrasound echo changes occur in tendon during viscoelastic testing.
Time-dependent ultrasound echo changes occur in tendon during viscoelastic testing.
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在粘弹性测试期间，肌腱中会发生随时间变化的超声回波变化。
DOI：
10.1115/1.4007745
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发表时间：
2012
期刊：
影响因子：
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通讯作者：
VanderbyJr,Ray
中科院分区：
文献类型：
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作者：
Duenwald-Kuehl,Sarah;Kobayashi,Hirohito;Lakes,Roderic;VanderbyJr,Ray
肌腱的粘弹性行为已经在体外得到了广泛的研究。一个非侵入性的方法，通过它来获取机械数据将是非常有益的，因为它可以导致在体内的粘弹性数据的收集。我们的实验室之前已经提出声弹性作为测量肌腱应力和应变的替代的基于超声的方法，其通过报告超声回波强度（B模式超声图像亮度）与体外条件下肌腱的机械行为之间的关系[Duenwald，S.，小林，Frisch，K.，湖泊河，和小范德比2011年，“超声回波与肌腱中的应力和应变有关”，J. Biomech.，44（3），pp. 424-429]。在该研究中没有检查肌腱的粘弹性，因此尚未验证是否存在随时间变化的回波强度变化。在这项研究中，猪屈肌腱进行松弛和循环测试，同时记录超声回波响应。我们报告，时间和应变历史依赖的粘弹性测试过程中的机械性能表现在超声回波强度的变化。我们还报告说，回波强度变化的模式不直接模仿粘弹性负载变化的模式，但强度以可重复的（因此可预测的）方式变化。虽然机制需要进一步阐明，粘弹性行为可以预期从回声强度的变化。这种现象可能导致更广泛的体内组织行为表征。
The viscoelastic behavior of tendons has been extensively studied in vitro. A noninvasive method by which to acquire mechanical data would be highly beneficial, as it could lead to the collection of viscoelastic data in vivo. Our lab has previously presented acoustoelasticity as an alternative ultrasound-based method of measuring tendon stress and strain by reporting a relationship between ultrasonic echo intensity (B mode ultrasound image brightness) and mechanical behavior of tendon under pseudoelastic in vitro conditions [Duenwald, S., Kobayashi, H., Frisch, K., Lakes, R., and Vanderby Jr, R., 2011, “Ultrasound Echo is Related to Stress and Strain in Tendon,” J. Biomech.,44(3), pp. 424–429]. Viscoelastic properties of the tendons were not examined in that study, so the presence of time-dependent echo intensity changes has not been verified. In this study, porcine flexor tendons were subjected to relaxation and cyclic testing while ultrasonic echo response was recorded. We report that time- and strain history-dependent mechanical properties during viscoelastic testing are manifested in ultrasonic echo intensity changes. We also report that the patterns of the echo intensity changes do not directly mimic the patterns of viscoelastic load changes, but the intensity changed in a repeatable (and therefore predictable) fashion. Although mechanisms need further elucidation, viscoelastic behavior can be anticipated from echo intensity changes. This phenomenon could potentially lead to a more extensive characterization of in vivo tissue behavior.