ESTROGEN FORMATION BY ISOLATED PERFUSED RHESUS-MONKEY BRAIN
ESTROGEN FORMATION BY ISOLATED PERFUSED RHESUS-MONKEY BRAIN
复制标题
DOI:
10.1126/science.180.4090.1074
复制
发表时间:
1973-01-01
期刊:
影响因子:
56.9
通讯作者:
WHITE, RJ
中科院分区:
文献类型:
--
作者:
FLORES, F;NAFTOLIN, F;WHITE, RJ
Perfusion of two isolated brains from immature male rhesus monkeys with [3H]androstenedione resulted in the identification of free and conjugated [3H]estrone and free [3H]estradiol from the perfusates. In the dissected cerebral tissues, estrogens were recovered only from the hypothalamus and limbic system. The production of estrogens from androstenedione during the 40-minute perfusions in these two experiments totaled 1.58 and 2.83 nanograms.