A sensitive colorimetric and fluorescent probe based on a polythiophene derivative for the detection of ATP
A sensitive colorimetric and fluorescent probe based on a polythiophene derivative for the detection of ATP
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DOI：
10.1002/anie.200501823
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发表时间：
2005-01-01
影响因子：
16.6
通讯作者：
Shinkai, S
中科院分区：
文献类型：
--
作者：
Li, C;Numata, M;Shinkai, S
从琥珀色到红色：水溶性聚噻吩衍生物1通过静电和疏水协同相互作用与ATP（三磷酸腺苷）形成超分子复合物，这导致水溶液的颜色从黄色变为粉红色（参见照片; AMP/ADP=单磷酸腺苷/二磷酸腺苷）。除了肉眼检测ATP外，通过使用荧光测定法，检测限可扩展至10-8 M。（化学方程式）
From amber to red: The water-soluble polythiophene derivative 1 forms a supramolecular complex with ATP (adenosine triphosphate) through electrostatic and hydrophobic cooperative interactions which results in a color change of the aqueous solution from yellow to pink-red (see photo; AMP/ADP= adenosine mono-/diphosphate). Besides naked-eye detection of ATP, the detection limit may be extended to 10-8 M by using fluorometry.(Chemical Equation Presented)