Physical activity dose-response effects on outcomes of depression and anxiety
Physical activity dose-response effects on outcomes of depression and anxiety
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DOI：
10.1097/00005768-200106001-00027
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发表时间：
2001-06-01
影响因子：
4.1
通讯作者：
O'Neal, HA
中科院分区：
文献类型：
--
作者：
Dunn, AL;Trivedi, MH;O'Neal, HA
目的：本研究的目的是检验体力活动与抑郁症和焦虑症的剂量反应关系的科学证据。研究方法：计算机数据库检索MEDLINE，PsychLit，互联网和个人检索系统，以找到人口研究，随机对照试验（RCT），观察性研究，和共识小组的判断进行。结果如下：观察性研究表明，更多的职业和休闲时间的身体活动通常与抑郁症状的减轻有关。准实验研究表明，轻度、中度和剧烈运动可以减轻抑郁症状。然而，在抑郁症或焦虑症的研究中，没有随机对照试验有不同的运动频率或持续时间，并控制了总能量消耗。准实验和随机对照试验表明，阻力训练和有氧运动都可以减轻抑郁症状。最后，运动剂量与心肺适能变化的关系是模棱两可的，一些研究表明聊天适能与症状减轻有关，而另一些研究表明症状减轻而不增加适能。结论：体力活动和运动的剂量反应效应的所有证据来自B和C证据水平。几乎没有剂量反应效应的证据，尽管这主要是因为缺乏研究而不是缺乏证据。然而，剂量-反应关系仍然合理。
Purpose: The purpose of this study was to examine the scientific evidence for a dose-response relation of physical activity with depressive and anxiety disorders. Methods: Computer database searches of MEDLINE, PsychLit, and Internet and personal retrieval systems to locate population studies, randomized controlled trials (RCTs), observational studies, and consensus panel judgments were conducted. Results: Observational studies demonstrate that greater amounts of occupational and leisure time physical activity are generally associated with reduced symptoms of depression. Quasi-experimental studies show that light-, moderate-, and vigorous-intensify exercise can reduce symptoms of depression. However, no RCTs have varied frequency or duration of exercise and controlled for total energy expenditure in studies of depression or anxiety. Quasi-experimental and RCTs demonstrate that both resistance training and aerobic exercise can reduce symptoms of depression. Finally, the relation of exercise dose to changes in cardiorespiratory fitness is equivocal with some studies showing Chat fitness is associated with reduction of symptoms and others that have demonstrated reduction in symptoms without increases in fitness. Conclusion: All evidence for dose-response effects of physical activity and exercise come from B and C levels of evidence. There is little evidence for dose-response effects, though this is largely because of a lack of studies rather than a lack of evidence. A dose-response relation does, however, remain plausible.