The generation of life events in recurrent and non-recurrent depression
The generation of life events in recurrent and non-recurrent depression
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复发性和非复发性抑郁症中生活事件的产生
DOI：
10.1017/s0033291798007752
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发表时间：
1999-01-01
影响因子：
6.9
通讯作者：
Thase, M
中科院分区：
文献类型：
--
作者：
Harkness, KL;Monroe, SM;Thase, M
背景。 Hammen（1991）提出的压力产生假说认为，抑郁的个体会为自己产生压力，从而导致复发。该假设的最初测试将患有复发性抑郁症的女性的依赖性生活事件与医疗和正常对照组进行了比较。这项工作提出了两个进一步的研究问题：（a）有多次抑郁发作史的个体是否比发作次数较少的抑郁症患者产生更多的依赖性生活事件？ (b) 可能产生的任何压力的病因学相关性是什么？方法。本研究测试了经历过以下情况的抑郁症患者之间依赖性事件和独立事件的差异：(a) 以前没有严重抑郁发作； (b) 之前的一集； (c) 之前的两集或更多集。我们预测，根据压力产生假说，复发性抑郁症患者会比没有抑郁症病史的人表现出更多的依赖性事件，并且这些产生的压力源对于诱发复发（即复发前 3 个月内的严重事件）具有重要的病因学意义。结果。复发性抑郁症患者在 12 个月内经历的总依赖性事件明显多于首次发作的抑郁症患者，但在发作前的 3 个月内则不然。结论。尽管研究结果支持了压力产生的一般前提，但所产生的压力与复发的病因学相关性需要进一步研究。
Background. The stress generation hypothesis proposed by Hammen (1991) holds that depressed individuals generate stressful conditions for themselves, which lead to recurrence. The original test of this hypothesis compared dependent life events in women with recurrent depression to medical and normal controls. Two further research questions emerged from this work: (a) do individuals with a history of many depressive episodes generate more dependent life events than depressives with fewer episodes?; and (b) what is the aetiological relevance of any stress that may be generated?Methods. The present research tested differences in dependent and independent events between depressed individuals who had experienced: (a) no previous major depressive episodes; (b) one previous episode; and (c) two or more previous episodes. We predicted that, based on the stress generation hypothesis, recurrent depressives would show more dependent events than people without a depression history, and that these generated stressors would be of aetiological importance for precipitating recurrence (i.e. severe events in the 3 months preceding recurrence).Results. Recurrent depressives experienced significantly more total dependent events than first-onset depressives in the 12 months, but not the 3 months, preceding their episode.Conclusions. Although the findings supported the general premise of stress generation, the aetiological relevance of the generated stress for recurrence requires further study.