The Preterm Prediction Study:: The value of serum alkaline phosphatase, α-fetoprotein, plasma corticotropin-releasing hormone, and other serum markers for the prediction of spontaneous preterm birth
The Preterm Prediction Study:: The value of serum alkaline phosphatase, α-fetoprotein, plasma corticotropin-releasing hormone, and other serum markers for the prediction of spontaneous preterm birth
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DOI：
10.1067/mob.2002.121727
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发表时间：
2002-05-01
影响因子：
9.8
通讯作者：
Roberts, JM
中科院分区：
文献类型：
--
作者：
Moawad, AH;Goldenberg, RL;Roberts, JM
目的：在母体血液中发现多种分析物含量较高；碱性磷酸酶、甲胎蛋白和促肾上腺皮质激素释放激素与自发性早产有关。我们调查了无症状孕妇的 8 种潜在血液标志物与随后的自发性早产之间的关系。 研究设计：我们进行了一项巢式病例对照研究，该研究涉及 127 名参加早产预测研究且在 2019 年发生单胎自发性早产的妇女。
OBJECTIVE: High levels of a number of analytes are found in maternal blood; alkaline phosphatase, alpha-fetoprotein, and corticotropin-releasing hormone have been associated with spontaneous preterm birth. We investigated the relationship between 8 potential blood markers and subsequent spontaneous preterm birth in asymptomatic pregnant women.STUDY DESIGN: We performed a nested case control study that involved 127 women who were enrolled in the preterm prediction study and who had a singleton spontaneous preterm birth at